Concise synthesis of α-cyano tetrahydroisoquinolines with a quaternary center via Strecker reaction

A concise synthesis of α-cyano tetrahydroisoquinolines with a quaternary center via the Strecker reaction was successfully realized by employing TMSCN as cyano source and KF as fluoride source, furnishing the products with up to 99% yield. An isomerization of α-cyano tetrahydroisoquinoline was obser...

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Detalles Bibliográficos
Autores principales: Ji, Yue, Zhang, Xue, Han, Weiwei, Wang, Sichang, Wu, Ya, Zhang, Keliang, Yang, Penghui, Xiao, Pei, Wei, Yitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044453/
https://www.ncbi.nlm.nih.gov/pubmed/35493240
http://dx.doi.org/10.1039/d1ra08469k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044453/
https://www.ncbi.nlm.nih.gov/pubmed/35493240
http://dx.doi.org/10.1039/d1ra08469k

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