Cp(2)ZrCl(2) – Et(3)Al reagent system in the homo-coupling of trimethylsilyl-substituted alkynes

The reaction of trimethylsilyl-substituted alkynes with 0.5 equivalents of Cp(2)ZrCl(2) and 1 equivalent of Et(3)Al in toluene at room temperature for 18 hours gives, after hydrolysis/deuterolysis or iodination, functionalized products of the homo-coupling of silyl-substituted alkynes in good yield....

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Detalles Bibliográficos
Autores principales: Ramazanov, Ilfir R., Kadikova, Rita N., Amirova, Aliya K., Mozgovoj, Oleg S., Dzhemilev, Usein M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044544/
https://www.ncbi.nlm.nih.gov/pubmed/35492468
http://dx.doi.org/10.1039/d1ra08268j
Descripción
Sumario:The reaction of trimethylsilyl-substituted alkynes with 0.5 equivalents of Cp(2)ZrCl(2) and 1 equivalent of Et(3)Al in toluene at room temperature for 18 hours gives, after hydrolysis/deuterolysis or iodination, functionalized products of the homo-coupling of silyl-substituted alkynes in good yield. Trimethylsilyl-substituted α,ω-diynes react with the Cp(2)ZrCl(2) – Et(3)Al reagent system to give (1Z,2Z)-1,2-bis(iodo(trimethylsilyl)methylene)cycloalkanes after iodinolysis.

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