Cp(2)ZrCl(2) – Et(3)Al reagent system in the homo-coupling of trimethylsilyl-substituted alkynes

The reaction of trimethylsilyl-substituted alkynes with 0.5 equivalents of Cp(2)ZrCl(2) and 1 equivalent of Et(3)Al in toluene at room temperature for 18 hours gives, after hydrolysis/deuterolysis or iodination, functionalized products of the homo-coupling of silyl-substituted alkynes in good yield....

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Autores principales: Ramazanov, Ilfir R., Kadikova, Rita N., Amirova, Aliya K., Mozgovoj, Oleg S., Dzhemilev, Usein M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044544/
https://www.ncbi.nlm.nih.gov/pubmed/35492468
http://dx.doi.org/10.1039/d1ra08268j
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author Ramazanov, Ilfir R.
Kadikova, Rita N.
Amirova, Aliya K.
Mozgovoj, Oleg S.
Dzhemilev, Usein M.
author_facet Ramazanov, Ilfir R.
Kadikova, Rita N.
Amirova, Aliya K.
Mozgovoj, Oleg S.
Dzhemilev, Usein M.
author_sort Ramazanov, Ilfir R.
collection PubMed
description The reaction of trimethylsilyl-substituted alkynes with 0.5 equivalents of Cp(2)ZrCl(2) and 1 equivalent of Et(3)Al in toluene at room temperature for 18 hours gives, after hydrolysis/deuterolysis or iodination, functionalized products of the homo-coupling of silyl-substituted alkynes in good yield. Trimethylsilyl-substituted α,ω-diynes react with the Cp(2)ZrCl(2) – Et(3)Al reagent system to give (1Z,2Z)-1,2-bis(iodo(trimethylsilyl)methylene)cycloalkanes after iodinolysis.
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spelling pubmed-90445442022-04-28 Cp(2)ZrCl(2) – Et(3)Al reagent system in the homo-coupling of trimethylsilyl-substituted alkynes Ramazanov, Ilfir R. Kadikova, Rita N. Amirova, Aliya K. Mozgovoj, Oleg S. Dzhemilev, Usein M. RSC Adv Chemistry The reaction of trimethylsilyl-substituted alkynes with 0.5 equivalents of Cp(2)ZrCl(2) and 1 equivalent of Et(3)Al in toluene at room temperature for 18 hours gives, after hydrolysis/deuterolysis or iodination, functionalized products of the homo-coupling of silyl-substituted alkynes in good yield. Trimethylsilyl-substituted α,ω-diynes react with the Cp(2)ZrCl(2) – Et(3)Al reagent system to give (1Z,2Z)-1,2-bis(iodo(trimethylsilyl)methylene)cycloalkanes after iodinolysis. The Royal Society of Chemistry 2021-12-13 /pmc/articles/PMC9044544/ /pubmed/35492468 http://dx.doi.org/10.1039/d1ra08268j Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Ramazanov, Ilfir R.
Kadikova, Rita N.
Amirova, Aliya K.
Mozgovoj, Oleg S.
Dzhemilev, Usein M.
Cp(2)ZrCl(2) – Et(3)Al reagent system in the homo-coupling of trimethylsilyl-substituted alkynes
title Cp(2)ZrCl(2) – Et(3)Al reagent system in the homo-coupling of trimethylsilyl-substituted alkynes
title_full Cp(2)ZrCl(2) – Et(3)Al reagent system in the homo-coupling of trimethylsilyl-substituted alkynes
title_fullStr Cp(2)ZrCl(2) – Et(3)Al reagent system in the homo-coupling of trimethylsilyl-substituted alkynes
title_full_unstemmed Cp(2)ZrCl(2) – Et(3)Al reagent system in the homo-coupling of trimethylsilyl-substituted alkynes
title_short Cp(2)ZrCl(2) – Et(3)Al reagent system in the homo-coupling of trimethylsilyl-substituted alkynes
title_sort cp(2)zrcl(2) – et(3)al reagent system in the homo-coupling of trimethylsilyl-substituted alkynes
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044544/
https://www.ncbi.nlm.nih.gov/pubmed/35492468
http://dx.doi.org/10.1039/d1ra08268j
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