Folic acid and deoxycholic acid derivative modified Fe(3)O(4) nanoparticles for efficient pH-dependent drug release and multi-targeting against liver cancer cells

The novel nano-drug carrier (FDCA-FA-MNPs) was constructed by grafting formyl deoxycholic acid (FDCA) and folic acid (FA) on the surface of Fe(3)O(4) magnetic nanoparticles (MNPs), possessing the advantages of superparamagnetism, good stability, low cytotoxicity and good blood compatibility. The hyd...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoyu, Ma, Qing, Wen, Chaochao, Gong, Tao, Li, Jing, Liang, Wenting, Li, Meining, Wang, Yuyao, Guo, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044570/
https://www.ncbi.nlm.nih.gov/pubmed/35494148
http://dx.doi.org/10.1039/d1ra05874f

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