An EHMT2/NFYA-ALDH2 signaling axis modulates the RAF pathway to regulate paclitaxel resistance in lung cancer

BACKGROUND: Lung cancer is a kind of malignancy with high morbidity and mortality worldwide. Paclitaxel (PTX) is the main treatment for non-small cell lung cancer (NSCLC), and resistance to PTX seriously affects the survival of patients. However, the underlying mechanism and potential reversing stra...

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Detalles Bibliográficos
Autores principales: Wang, Wenjing, Wang, Jianmin, Liu, Shuai, Ren, Yong, Wang, Jingyu, Liu, Sen, Cui, Wei, Jia, Lina, Tang, Xing, Yang, Jingyu, Wu, Chunfu, Wang, Lihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044593/
https://www.ncbi.nlm.nih.gov/pubmed/35477569
http://dx.doi.org/10.1186/s12943-022-01579-9

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