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Structure based innovative approach to analyze aptaprobe–GPC3 complexes in hepatocellular carcinoma

BACKGROUND: Glypican-3 (GPC3), a membrane-bound heparan sulfate proteoglycan, is a biomarker of hepatocellular carcinoma (HCC) progression. Aptamers specifically binding to target biomolecules have recently emerged as clinical disease diagnosis targets. Here, we describe 3D structure-based aptaprobe...

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Detalles Bibliográficos
Autores principales:	Shin, Woo-Ri, Park, Dae-Young, Kim, Ji Hun, Lee, Jin-Pyo, Thai, Nguyen Quang, Oh, In-Hwan, Sekhon, Simranjeet Singh, Choi, Wooil, Kim, Sung Yeon, Cho, Byung-Kwan, Kim, Sun Chang, Min, Jiho, Ahn, Ji-Young, Kim, Yang-Hoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044640/ https://www.ncbi.nlm.nih.gov/pubmed/35477501 http://dx.doi.org/10.1186/s12951-022-01391-z

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