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Diosmin mitigates high glucose-induced endoplasmic reticulum stress through PI3K/AKT pathway in HK-2 cells

BACKGROUND: Diosmin has been reported to treat diabetes, but its role in diabetic nephropathy (DN) remains unclear. This research investigated the mechanism by which diosmin alleviated high glucose (HG)-induced HK-2 cell injury. METHODS: First, we used CCK-8 to detect the effect of 0.1, 1, or 10 μg/...

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Detalles Bibliográficos
Autores principales:	Deng, Jiuhong, Zheng, Chao, Hua, Zhou, Ci, Haideng, Wang, Guiying, Chen, Lijing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044681/ https://www.ncbi.nlm.nih.gov/pubmed/35477428 http://dx.doi.org/10.1186/s12906-022-03597-y

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