Synthetic lethality-based prediction of anti-SARS-CoV-2 targets

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Novel strategies are needed to identify drug targets and treatments for the COVID-19 pandemic. The altered gene expression of virus-infected host cells provides an opportunity to specifically inhibit viral propagation via targeting the synthetic lethal and synthetic dosage lethal (SL/SDL) partners o...

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Detalles Bibliográficos
Autores principales: Pal, Lipika R., Cheng, Kuoyuan, Nair, Nishanth Ulhas, Martin-Sancho, Laura, Sinha, Sanju, Pu, Yuan, Riva, Laura, Yin, Xin, Schischlik, Fiorella, Lee, Joo Sang, Chanda, Sumit K., Ruppin, Eytan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044693/
https://www.ncbi.nlm.nih.gov/pubmed/35502318
http://dx.doi.org/10.1016/j.isci.2022.104311
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