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High rates of undiagnosed and uncontrolled hypertension upon a screening campaign in rural Rwanda: a cross-sectional study

BACKGROUND: Hypertension remains the major risk factor for cardiovascular diseases (CVDs) worldwide with a prevalence and mortality in low- and middle-income countries (LMICs) among the highest. The early detection of hypertension risk factors is a crucial pillar for CVD prevention. DESIGN AND METHO...

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Autores principales: Ntaganda, Evariste, Mugeni, Regine, Harerimana, Emmanuel, Ngoga, Gedeon, Dusabeyezu, Symaque, Uwinkindi, Francois, Utumatwishima, Jean N., Mutimura, Eugene, Davila-Roman, Victor G., Schechtman, Kenneth, Nishimwe, Aurore, Twizeyimana, Laurence, Brown, Angela L., Cade, W. Todd, Bushaku, Marcus, de Las Fuentes, Lisa, Reeds, Dominic, Twagirumukiza, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044706/
https://www.ncbi.nlm.nih.gov/pubmed/35473501
http://dx.doi.org/10.1186/s12872-022-02606-9
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author Ntaganda, Evariste
Mugeni, Regine
Harerimana, Emmanuel
Ngoga, Gedeon
Dusabeyezu, Symaque
Uwinkindi, Francois
Utumatwishima, Jean N.
Mutimura, Eugene
Davila-Roman, Victor G.
Schechtman, Kenneth
Nishimwe, Aurore
Twizeyimana, Laurence
Brown, Angela L.
Cade, W. Todd
Bushaku, Marcus
de Las Fuentes, Lisa
Reeds, Dominic
Twagirumukiza, Marc
author_facet Ntaganda, Evariste
Mugeni, Regine
Harerimana, Emmanuel
Ngoga, Gedeon
Dusabeyezu, Symaque
Uwinkindi, Francois
Utumatwishima, Jean N.
Mutimura, Eugene
Davila-Roman, Victor G.
Schechtman, Kenneth
Nishimwe, Aurore
Twizeyimana, Laurence
Brown, Angela L.
Cade, W. Todd
Bushaku, Marcus
de Las Fuentes, Lisa
Reeds, Dominic
Twagirumukiza, Marc
author_sort Ntaganda, Evariste
collection PubMed
description BACKGROUND: Hypertension remains the major risk factor for cardiovascular diseases (CVDs) worldwide with a prevalence and mortality in low- and middle-income countries (LMICs) among the highest. The early detection of hypertension risk factors is a crucial pillar for CVD prevention. DESIGN AND METHOD: This cross-sectional study included 4284 subjects, mean age 46 ± 16SD, 56.4% females and mean BMI 26.6 ± 3.7 SD. Data were collected through a screening campaign in rural area of Kirehe District, Eastern of Rwanda, with the objective to characterize and examine the prevalence of elevated blood pressure (BP) and other CVD risk factors. An adapted tool from the World Health Organization STEPwise Approach was used for data collection. Elevated BP was defined as ≥ 140/90 mm/Hg and elevated blood glucose as blood glucose ≥ 100 mg/dL after a 6-h fast. RESULTS: Of the sampled population, 21.2% (n = 910) had an elevated BP at screening; BP was elevated among individuals not previously known to have HTN in 18.7% (n = 752). Among individuals with a prior diagnosis of HTN, 62.2% (n = 158 of 254) BP was uncontrolled. Age, weight, smoking, alcohol history and waist circumference were associated with BP in both univariate analyses and multivariate analysis. CONCLUSION: High rates of elevated BP identified through a health screening campaign in this Rwandan district were surprising given the rural characteristics of the district and relatively low population age. These data highlight the need to implement an adequate strategy for the prevention, diagnosis, and control of HTN that includes rural areas of Rwanda as part of a multicomponent strategy for CVD prevention. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12872-022-02606-9.
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spelling pubmed-90447062022-04-28 High rates of undiagnosed and uncontrolled hypertension upon a screening campaign in rural Rwanda: a cross-sectional study Ntaganda, Evariste Mugeni, Regine Harerimana, Emmanuel Ngoga, Gedeon Dusabeyezu, Symaque Uwinkindi, Francois Utumatwishima, Jean N. Mutimura, Eugene Davila-Roman, Victor G. Schechtman, Kenneth Nishimwe, Aurore Twizeyimana, Laurence Brown, Angela L. Cade, W. Todd Bushaku, Marcus de Las Fuentes, Lisa Reeds, Dominic Twagirumukiza, Marc BMC Cardiovasc Disord Research BACKGROUND: Hypertension remains the major risk factor for cardiovascular diseases (CVDs) worldwide with a prevalence and mortality in low- and middle-income countries (LMICs) among the highest. The early detection of hypertension risk factors is a crucial pillar for CVD prevention. DESIGN AND METHOD: This cross-sectional study included 4284 subjects, mean age 46 ± 16SD, 56.4% females and mean BMI 26.6 ± 3.7 SD. Data were collected through a screening campaign in rural area of Kirehe District, Eastern of Rwanda, with the objective to characterize and examine the prevalence of elevated blood pressure (BP) and other CVD risk factors. An adapted tool from the World Health Organization STEPwise Approach was used for data collection. Elevated BP was defined as ≥ 140/90 mm/Hg and elevated blood glucose as blood glucose ≥ 100 mg/dL after a 6-h fast. RESULTS: Of the sampled population, 21.2% (n = 910) had an elevated BP at screening; BP was elevated among individuals not previously known to have HTN in 18.7% (n = 752). Among individuals with a prior diagnosis of HTN, 62.2% (n = 158 of 254) BP was uncontrolled. Age, weight, smoking, alcohol history and waist circumference were associated with BP in both univariate analyses and multivariate analysis. CONCLUSION: High rates of elevated BP identified through a health screening campaign in this Rwandan district were surprising given the rural characteristics of the district and relatively low population age. These data highlight the need to implement an adequate strategy for the prevention, diagnosis, and control of HTN that includes rural areas of Rwanda as part of a multicomponent strategy for CVD prevention. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12872-022-02606-9. BioMed Central 2022-04-26 /pmc/articles/PMC9044706/ /pubmed/35473501 http://dx.doi.org/10.1186/s12872-022-02606-9 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Ntaganda, Evariste
Mugeni, Regine
Harerimana, Emmanuel
Ngoga, Gedeon
Dusabeyezu, Symaque
Uwinkindi, Francois
Utumatwishima, Jean N.
Mutimura, Eugene
Davila-Roman, Victor G.
Schechtman, Kenneth
Nishimwe, Aurore
Twizeyimana, Laurence
Brown, Angela L.
Cade, W. Todd
Bushaku, Marcus
de Las Fuentes, Lisa
Reeds, Dominic
Twagirumukiza, Marc
High rates of undiagnosed and uncontrolled hypertension upon a screening campaign in rural Rwanda: a cross-sectional study
title High rates of undiagnosed and uncontrolled hypertension upon a screening campaign in rural Rwanda: a cross-sectional study
title_full High rates of undiagnosed and uncontrolled hypertension upon a screening campaign in rural Rwanda: a cross-sectional study
title_fullStr High rates of undiagnosed and uncontrolled hypertension upon a screening campaign in rural Rwanda: a cross-sectional study
title_full_unstemmed High rates of undiagnosed and uncontrolled hypertension upon a screening campaign in rural Rwanda: a cross-sectional study
title_short High rates of undiagnosed and uncontrolled hypertension upon a screening campaign in rural Rwanda: a cross-sectional study
title_sort high rates of undiagnosed and uncontrolled hypertension upon a screening campaign in rural rwanda: a cross-sectional study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044706/
https://www.ncbi.nlm.nih.gov/pubmed/35473501
http://dx.doi.org/10.1186/s12872-022-02606-9
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