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RAGE signaling during tobacco smoke-induced lung inflammation and potential therapeutic utility of SAGEs

BACKGROUND: Smoke exposure culminates as a progressive lung complication involving airway inflammation and remodeling. While primary smoke poses the greatest risk, nearly half of the US population is also at risk due to exposure to secondhand smoke (SHS). METHODS: We used WT, RAGE−/− (KO), and Tet-i...

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Detalles Bibliográficos
Autores principales: Hirschi-Budge, Kelsey M., Tsai, Kary Y. F., Curtis, Katrina L., Davis, Gregg S., Theurer, Benjamin K., Kruyer, Anica M. M., Homer, Kyle W., Chang, Ashley, Van Ry, Pam M., Arroyo, Juan A., Reynolds, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044720/
https://www.ncbi.nlm.nih.gov/pubmed/35473605
http://dx.doi.org/10.1186/s12890-022-01935-x

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