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Association between quality of life and mental stress-induced myocardial ischaemia in high-risk patients after coronary revascularization

OBJECTIVE: We sought to determine the association between mental stress-induced myocardial ischaemia (MSIMI) and quality of life (QoL) in patients with coronary artery disease (CAD) after coronary revascularization. METHODS: This cohort study involved patients with high-risk MSIMI who received coron...

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Autores principales: Nan, Nan, Dong, Wei, Gao, Bingyu, Cui, Feihuan, Chang, Zhi, Jiao, Jian, Zuo, Huijuan, Mi, Hongzhi, Song, Xiantao, Lyu, Shuzheng, Zhang, Hongjia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044723/
https://www.ncbi.nlm.nih.gov/pubmed/35473557
http://dx.doi.org/10.1186/s12955-022-01976-0
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author Nan, Nan
Dong, Wei
Gao, Bingyu
Cui, Feihuan
Chang, Zhi
Jiao, Jian
Zuo, Huijuan
Mi, Hongzhi
Song, Xiantao
Lyu, Shuzheng
Zhang, Hongjia
author_facet Nan, Nan
Dong, Wei
Gao, Bingyu
Cui, Feihuan
Chang, Zhi
Jiao, Jian
Zuo, Huijuan
Mi, Hongzhi
Song, Xiantao
Lyu, Shuzheng
Zhang, Hongjia
author_sort Nan, Nan
collection PubMed
description OBJECTIVE: We sought to determine the association between mental stress-induced myocardial ischaemia (MSIMI) and quality of life (QoL) in patients with coronary artery disease (CAD) after coronary revascularization. METHODS: This cohort study involved patients with high-risk MSIMI who received coronary revascularization between Dec 2018 and Dec 2019. Patients who screened positive for depression/anxiety were enrolled in this study. Mental stress was induced by the Stroop Colour and Word Test 1 month after coronary revascularization. All participants underwent single photon emission computed tomography (SPECT) scans at rest and under mental stress. MSIMI was defined as the presence of four abnormal SPECT phenomena. QoL was assessed using the Seattle Angina Questionnaire (SAQ) prior to treatment and 1 month after coronary revascularization. RESULTS: Of the 1845 consecutive patients who received coronary revascularization, 590 (31.9%) had depression/anxiety, and 205 agreed to accept the mental stress test. During the average observation period of 33 days, 105 (51.2%) patients exhibited MSIMI. All SAQ subscales showed significant improvement, except for QoL, in the MSIMI group. The QoL score was lower (− 0.2 ± 32.7 vs. 13.1 ± 29.9, P = 0.005), and the proportion of deterioration in QoL was higher (50.5% vs. 31.9%, P = 0.010) in the MSIMI group than in the non-MSIMI group. Those with a deterioration in QoL had approximately twice the rate of MSIMI than those with an improvement in QoL (unadjusted OR: 2.019, 95% CI 1.122–3.634, P = 0.026; adjusted OR: 1.968, 95% CI 1.083–3.578, P = 0.017). CONCLUSION: Among patients with CAD who received coronary revascularization and had depression/anxiety, deterioration in QoL increased the likelihood of MSIMI. Hence, our results indicate that deterioration in QoL is a predictor of MSIMI. Trail Registration ChiCTR2200055792, retrospectively registered, 2022.1.20, www.medresman.org.cn
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spelling pubmed-90447232022-04-28 Association between quality of life and mental stress-induced myocardial ischaemia in high-risk patients after coronary revascularization Nan, Nan Dong, Wei Gao, Bingyu Cui, Feihuan Chang, Zhi Jiao, Jian Zuo, Huijuan Mi, Hongzhi Song, Xiantao Lyu, Shuzheng Zhang, Hongjia Health Qual Life Outcomes Research OBJECTIVE: We sought to determine the association between mental stress-induced myocardial ischaemia (MSIMI) and quality of life (QoL) in patients with coronary artery disease (CAD) after coronary revascularization. METHODS: This cohort study involved patients with high-risk MSIMI who received coronary revascularization between Dec 2018 and Dec 2019. Patients who screened positive for depression/anxiety were enrolled in this study. Mental stress was induced by the Stroop Colour and Word Test 1 month after coronary revascularization. All participants underwent single photon emission computed tomography (SPECT) scans at rest and under mental stress. MSIMI was defined as the presence of four abnormal SPECT phenomena. QoL was assessed using the Seattle Angina Questionnaire (SAQ) prior to treatment and 1 month after coronary revascularization. RESULTS: Of the 1845 consecutive patients who received coronary revascularization, 590 (31.9%) had depression/anxiety, and 205 agreed to accept the mental stress test. During the average observation period of 33 days, 105 (51.2%) patients exhibited MSIMI. All SAQ subscales showed significant improvement, except for QoL, in the MSIMI group. The QoL score was lower (− 0.2 ± 32.7 vs. 13.1 ± 29.9, P = 0.005), and the proportion of deterioration in QoL was higher (50.5% vs. 31.9%, P = 0.010) in the MSIMI group than in the non-MSIMI group. Those with a deterioration in QoL had approximately twice the rate of MSIMI than those with an improvement in QoL (unadjusted OR: 2.019, 95% CI 1.122–3.634, P = 0.026; adjusted OR: 1.968, 95% CI 1.083–3.578, P = 0.017). CONCLUSION: Among patients with CAD who received coronary revascularization and had depression/anxiety, deterioration in QoL increased the likelihood of MSIMI. Hence, our results indicate that deterioration in QoL is a predictor of MSIMI. Trail Registration ChiCTR2200055792, retrospectively registered, 2022.1.20, www.medresman.org.cn BioMed Central 2022-04-26 /pmc/articles/PMC9044723/ /pubmed/35473557 http://dx.doi.org/10.1186/s12955-022-01976-0 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visithttp://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Nan, Nan
Dong, Wei
Gao, Bingyu
Cui, Feihuan
Chang, Zhi
Jiao, Jian
Zuo, Huijuan
Mi, Hongzhi
Song, Xiantao
Lyu, Shuzheng
Zhang, Hongjia
Association between quality of life and mental stress-induced myocardial ischaemia in high-risk patients after coronary revascularization
title Association between quality of life and mental stress-induced myocardial ischaemia in high-risk patients after coronary revascularization
title_full Association between quality of life and mental stress-induced myocardial ischaemia in high-risk patients after coronary revascularization
title_fullStr Association between quality of life and mental stress-induced myocardial ischaemia in high-risk patients after coronary revascularization
title_full_unstemmed Association between quality of life and mental stress-induced myocardial ischaemia in high-risk patients after coronary revascularization
title_short Association between quality of life and mental stress-induced myocardial ischaemia in high-risk patients after coronary revascularization
title_sort association between quality of life and mental stress-induced myocardial ischaemia in high-risk patients after coronary revascularization
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044723/
https://www.ncbi.nlm.nih.gov/pubmed/35473557
http://dx.doi.org/10.1186/s12955-022-01976-0
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