2 deoxy-D-glucose augments the mitochondrial respiratory chain in heart

2-Deoxy-D-glucose (2DG) has recently received emergency approval for the treatment of COVID-19 in India, after a successful clinical trial. SARS-CoV-2 infection of cultured cells is accompanied by elevated glycolysis and decreased mitochondrial function, whereas 2DG represses glycolysis and stimulat...

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Detalles Bibliográficos
Autores principales: Aiestaran-Zelaia, Irati, Sánchez-Guisado, María Jesús, Villar-Fernandez, Marina, Azkargorta, Mikel, Fadon-Padilla, Lucia, Fernandez-Pelayo, Uxoa, Perez-Rodriguez, Diego, Ramos-Cabrer, Pedro, Spinazzola, Antonella, Elortza, Félix, Ruíz-Cabello, Jésus, Holt, Ian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044724/
https://www.ncbi.nlm.nih.gov/pubmed/35478201
http://dx.doi.org/10.1038/s41598-022-10168-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044724/
https://www.ncbi.nlm.nih.gov/pubmed/35478201
http://dx.doi.org/10.1038/s41598-022-10168-1

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