MicroRNA-146a-5p-modified human umbilical cord mesenchymal stem cells enhance protection against diabetic nephropathy in rats through facilitating M2 macrophage polarization

BACKGROUND: Diabetic nephropathy (DN) is a severe complication of diabetes mellitus and a common cause of end-stage renal disease (ESRD). Mesenchymal stem cells (MSCs) possess potent anti-inflammatory and immunomodulatory properties, which render them an attractive therapeutic tool for tissue damage...

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Detalles Bibliográficos
Autores principales: Zhang, Yaqi, Le, Xi, Zheng, Shuo, Zhang, Ke, He, Jing, Liu, Mengting, Tu, Chengshu, Rao, Wei, Du, Hongyuan, Ouyang, Yu, Li, Changyong, Wu, Dongcheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044847/
https://www.ncbi.nlm.nih.gov/pubmed/35477552
http://dx.doi.org/10.1186/s13287-022-02855-7

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