NFκB inhibition to lift the mechano-competence of mesenchymal stromal cell-derived neocartilage toward articular chondrocyte levels

BACKGROUND: Fully functional regeneration of skeletal defects by multipotent progenitor cells requires that differentiating cells gain the specific mechano-competence needed in the target tissue. Using cartilage neogenesis as an example, we asked whether proper phenotypic differentiation of mesenchy...

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Detalles Bibliográficos
Autores principales: Lückgen, Janine, Raqué, Elisabeth, Reiner, Tobias, Diederichs, Solvig, Richter, Wiltrud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044876/
https://www.ncbi.nlm.nih.gov/pubmed/35477424
http://dx.doi.org/10.1186/s13287-022-02843-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044876/
https://www.ncbi.nlm.nih.gov/pubmed/35477424
http://dx.doi.org/10.1186/s13287-022-02843-x

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