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NFκB inhibition to lift the mechano-competence of mesenchymal stromal cell-derived neocartilage toward articular chondrocyte levels

BACKGROUND: Fully functional regeneration of skeletal defects by multipotent progenitor cells requires that differentiating cells gain the specific mechano-competence needed in the target tissue. Using cartilage neogenesis as an example, we asked whether proper phenotypic differentiation of mesenchy...

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Detalles Bibliográficos
Autores principales:	Lückgen, Janine, Raqué, Elisabeth, Reiner, Tobias, Diederichs, Solvig, Richter, Wiltrud
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044876/ https://www.ncbi.nlm.nih.gov/pubmed/35477424 http://dx.doi.org/10.1186/s13287-022-02843-x

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