Cargando…

Histone methyltransferase KMT2D cooperates with MEF2A to promote the stem-like properties of oral squamous cell carcinoma

BACKGROUND: Epigenetic reprogramming is involved in multiple steps of human cancer evolution and is mediated by a variety of chromatin-modifying enzymes. Specifically, the histone lysine methyltransferase KMT2D is among the most frequently mutated genes in oral squamous cell carcinoma (OSCC). Howeve...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Xinmiao, Li, Rui, Wu, Luping, Chen, Yang, Liu, Shaopeng, Zhao, Hui, Wang, Yifan, Wang, Lin, Shao, Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044881/
https://www.ncbi.nlm.nih.gov/pubmed/35477537
http://dx.doi.org/10.1186/s13578-022-00785-8