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The Stickland Reaction Precursor trans-4-Hydroxy-l-Proline Differentially Impacts the Metabolism of Clostridioides difficile and Commensal Clostridia

An intact gut microbiota confers colonization resistance against Clostridioides difficile through a variety of mechanisms, likely including competition for nutrients. Recently, proline was identified as an important environmental amino acid that C. difficile uses to support growth and cause signific...

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Detalles Bibliográficos
Autores principales:	Reed, A. D., Fletcher, J. R., Huang, Y. Y., Thanissery, R., Rivera, A. J., Parsons, R. J., Stewart, A. K., Kountz, D. J., Shen, A., Balskus, E. P., Theriot, C. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044972/ https://www.ncbi.nlm.nih.gov/pubmed/35350846 http://dx.doi.org/10.1128/msphere.00926-21

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