IL-6 Prevents Lung Macrophage Death and Lung Inflammation Injury by Inhibiting GSDME- and GSDMD-Mediated Pyroptosis during Pneumococcal Pneumosepsis

Streptococcus pneumoniae is a leading bacterial cause of a wide range of infections, and pneumococcal pneumosepsis causes high mortality in hosts infected with antibiotic-resistant strains and those who cannot resolve ongoing inflammation. The factors which influence the development and outcome of p...

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Detalles Bibliográficos
Autores principales: Gou, Xuemei, Xu, Wenchun, Liu, Yusi, Peng, Yang, Xu, Wenlong, Yin, Yibing, Zhang, Xuemei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045248/
https://www.ncbi.nlm.nih.gov/pubmed/35297653
http://dx.doi.org/10.1128/spectrum.02049-21

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