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Neutralizing Monoclonal Antibodies Inhibit SARS-CoV-2 Infection through Blocking Membrane Fusion

Most of SARS-CoV-2 neutralizing antibodies (nAbs) targeted the receptor binding domain (RBD) of the SARS-CoV-2 spike (S) protein. However, mutations at RBD sequences found in the emerging SARS-CoV-2 variants greatly reduced the effectiveness of nAbs. Here we showed that four nAbs, S2-4D, S2-5D, S2-8...

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Detalles Bibliográficos
Autores principales:	Li, Chia-Jung, Chao, Tai-Ling, Chang, Ting-Yu, Hsiao, Chia-Chun, Lu, De-Chao, Chiang, Yi-Wei, Lai, Guan-Chun, Tsai, Ya-Min, Fang, Jun-Tung, Ieong, Siman, Wang, Jann-Tay, Chang, Sui-Yuan, Chang, Shih-Chung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045258/ https://www.ncbi.nlm.nih.gov/pubmed/35293796 http://dx.doi.org/10.1128/spectrum.01814-21

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