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WhiB4 Is Required for the Reactivation of Persistent Infection of Mycobacterium marinum in Zebrafish

Granulomas are the pathological hallmark of tuberculosis (TB). In individuals with latent TB infection, Mycobacterium tuberculosis cells reside within granulomas in a nonreplicating dormant state, and a portion of them will develop active TB. Little is known on the bacterial mechanisms/factors invol...

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Detalles Bibliográficos
Autores principales: Lin, Chen, Tang, Yuting, Wang, Yuchen, Zhang, Junli, Li, Yeyu, Xu, Shuqin, Xia, Bin, Zhai, Qiran, Li, Yao, Zhang, Lu, Liu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045381/
https://www.ncbi.nlm.nih.gov/pubmed/35266819
http://dx.doi.org/10.1128/spectrum.00443-21