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Identification of a KPC Variant Conferring Resistance to Ceftazidime-Avibactam from ST11 Carbapenem-Resistant Klebsiella pneumoniae Strains

A novel Klebsiella pneumoniae carbapenemase (KPC) variant, KPC-93, was identified in two Klebsiella pneumoniae clinical isolates from a patient from China treated with ceftazidime-avibactam. KPC-93 possessed a five-amino-acids insertion (Pro-Asn-Asn-Arg-Ala) between Ambler positions 267 and 268 in K...

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Detalles Bibliográficos
Autores principales:	Wu, Yuchen, Yang, Xuemei, Liu, Congcong, Zhang, Yanyan, Cheung, Yan Chu, Wai Chi Chan, Edward, Chen, Sheng, Zhang, Rong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045388/ https://www.ncbi.nlm.nih.gov/pubmed/35416703 http://dx.doi.org/10.1128/spectrum.02655-21

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