Single Donor Infusion of S-Nitroso-Human-Serum-Albumin Attenuates Cardiac Isograft Fibrosis and Preserves Myocardial Micro-RNA-126-3p in a Murine Heterotopic Heart Transplant Model

Objectives: Cold ischemia and subsequent reperfusion injury are non-immunologic cornerstones in the development of graft injury after heart transplantation. The nitric oxide donor S-nitroso-human-serum-albumin (S-NO-HSA) is known to attenuate myocardial ischemia-reperfusion (I/R)-injury. We assessed...

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Detalles Bibliográficos
Autores principales: Schaefer, Anne-Kristin, Kiss, Attila, Oszwald, André, Nagel, Felix, Acar, Eylem, Aliabadi-Zuckermann, Arezu, Hackl, Matthias, Zuckermann, Andreas, Kain, Renate, Jakubowski, Andrzej, Ferdinandy, Peter, Hallström, Seth, Podesser, Bruno K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Health Archive
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045410/
https://www.ncbi.nlm.nih.gov/pubmed/35497886
http://dx.doi.org/10.3389/ti.2022.10057

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