Identification of four novel T cell autoantigens and personal autoreactive profiles in multiple sclerosis

Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS), in which pathological T cells, likely autoimmune, play a key role. Despite its central importance, the autoantigen repertoire remains largely uncharacterized. Using a novel in vitro antigen delivery method combin...

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Detalles Bibliográficos
Autores principales: Bronge, Mattias, Högelin, Klara Asplund, Thomas, Olivia G., Ruhrmann, Sabrina, Carvalho-Queiroz, Claudia, Nilsson, Ola B., Kaiser, Andreas, Zeitelhofer, Manuel, Holmgren, Erik, Linnerbauer, Mathias, Adzemovic, Milena Z., Hellström, Cecilia, Jelcic, Ivan, Liu, Hao, Nilsson, Peter, Hillert, Jan, Brundin, Lou, Fink, Katharina, Kockum, Ingrid, Tengvall, Katarina, Martin, Roland, Tegel, Hanna, Gräslund, Torbjörn, Al Nimer, Faiez, Guerreiro-Cacais, André Ortlieb, Khademi, Mohsen, Gafvelin, Guro, Olsson, Tomas, Grönlund, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045615/
https://www.ncbi.nlm.nih.gov/pubmed/35476434
http://dx.doi.org/10.1126/sciadv.abn1823

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