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Pan-cancer analysis of microRNA expression profiles highlights microRNAs enriched in normal body cells as effective suppressors of multiple tumor types: A study based on TCGA database

BACKGROUND: MicroRNAs (miRNAs) are frequently deregulated in various types of cancer. While antisense oligonucleotides are used to block oncomiRs, delivery of tumour-suppressive miRNAs holds great potential as a potent anti-cancer strategy. Here, we aim to determine, and functionally analyse, miRNAs...

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Detalles Bibliográficos
Autores principales: Moradi, Sharif, Kamal, Aryan, Aboulkheyr Es, Hamidreza, Farhadi, Farnoosh, Ebrahimi, Marzieh, Chitsaz, Hamidreza, Sharifi-Zarchi, Ali, Baharvand, Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045663/
https://www.ncbi.nlm.nih.gov/pubmed/35476804
http://dx.doi.org/10.1371/journal.pone.0267291