Cargando…

ETS1 acts as a regulator of human healthy aging via decreasing ribosomal activity

Adaptation to reduced energy production during aging is a fundamental issue for maintaining healthspan or prolonging life span. Currently, however, the underlying mechanism in long-lived people remains poorly understood. Here, we analyzed transcriptomes of 185 long-lived individuals (LLIs) and 86 sp...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xiao, Fu-Hui, Yu, Qin, Deng, Zhi-Li, Yang, Ke, Ye, Yunshuang, Ge, Ming-Xia, Yan, Dongjing, Wang, Hao-Tian, Chen, Xiao-Qiong, Yang, Li-Qin, Yang, Bin-Yu, Lin, Rong, Zhang, Wen, Yang, Xing-Li, Dong, Lei, He, Yonghan, Zhou, Jumin, Cai, Wang-Wei, Li, Ji, Kong, Qing-Peng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2022
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045719/ https://www.ncbi.nlm.nih.gov/pubmed/35476452 http://dx.doi.org/10.1126/sciadv.abf2017

Ejemplares similares

Hypermethylation in H3K9me3 regions characterizes the centenarian methylomes in healthy aging
por: Xiao, Fu-Hui, et al.
Publicado: (2023)

Transcriptome evidence reveals enhanced autophagy-lysosomal function in centenarians
por: Xiao, Fu-Hui, et al.
Publicado: (2018)

dNAGLU Extends Life Span and Promotes Fitness and Stress Resistance in Drosophila
por: Xue, Rubing, et al.
Publicado: (2022)

Multiple time-series expression trajectories imply dynamic functional changes during cellular senescence
por: Ge, Ming-Xia, et al.
Publicado: (2022)

Protein Restriction Effects on Healthspan and Lifespan in Drosophila melanogaster Are Additive With a Longevity-Promoting Diet
por: Zhang, Wei, et al.
Publicado: (2023)

The Ubx Polycomb response element bypasses an unpaired Fab-8 insulator via cis transvection in Drosophila
por: Lu, Danfeng, et al.
Publicado: (2018)

Longevity-Associated Transcription Factor ATF7 Promotes Healthspan by Suppressing Cellular Senescence and Systematic Inflammation
por: Huang, Yaqun, et al.
Publicado: (2023)

Genome-wide assessment of differential translations with ribosome profiling data
por: Xiao, Zhengtao, et al.
Publicado: (2016)

DV21 decreases excitability of cortical pyramidal neurons and acts in epilepsy
por: Xu, Min, et al.
Publicado: (2017)

Atg4b Overexpression Extends Lifespan and Healthspan in Drosophila melanogaster
por: Li, Yongxuan, et al.
Publicado: (2023)

Survey of the translation shifts in hepatocellular carcinoma with ribosome profiling
por: Zou, Qin, et al.
Publicado: (2019)

Cyclophilin acts as a ribosome biogenesis factor by chaperoning the ribosomal protein (PlRPS15) in filamentous fungi
por: Mo, Chenmi, et al.
Publicado: (2021)

LncRNA EGOT decreases breast cancer cell viability and migration via inactivation of the Hedgehog pathway
por: Qiu, Shuang, et al.
Publicado: (2020)

Heparanase from triple-negative breast cancer and platelets acts as an enhancer of metastasis
por: Yang, Wen-Jing, et al.
Publicado: (2020)

Metabolic healthy obesity is associated with higher incidence of mild decrease estimate glomerular rate in rural northeast Chinese
por: Yu, Shasha, et al.
Publicado: (2020)

Organization and expression analysis of 5S and 45S ribosomal DNA clusters in autotetraploid Carassius auratus
por: Zhao, Chun, et al.
Publicado: (2021)

Oryza sativa ObgC1 Acts as a Key Regulator of DNA Replication and Ribosome Biogenesis in Chloroplast Nucleoids
por: Chen, Ji, et al.
Publicado: (2021)

Norepinephrine Enhances Aerobic Glycolysis and May Act as a Predictive Factor for Immunotherapy in Gastric Cancer
por: Wang, Yangyang, et al.
Publicado: (2021)

GhWRKY6 Acts as a Negative Regulator in Both Transgenic Arabidopsis and Cotton During Drought and Salt Stress
por: Li, Zhi, et al.
Publicado: (2019)

Improved lipids, diastolic pressure and kidney function are potential contributors to familial longevity: a study on 60 Chinese centenarian families
por: He, Yong-Han, et al.
Publicado: (2016)

LINC02190 inhibits the embryo–endometrial attachment by decreasing ITGAD expression
por: Zhao, Feiyan, et al.
Publicado: (2022)

The M6A methyltransferase METTL3: acting as a tumor suppressor in renal cell carcinoma
por: Li, Xiao, et al.
Publicado: (2017)

Persistent inflammation and neuronal loss in the mouse brain induced by a modified form of attenuated herpes simplex virus type I
por: Wang, Erlin, et al.
Publicado: (2022)

Geridonin and paclitaxel act synergistically to inhibit the proliferation of gastric cancer cells through ROS-mediated regulation of the PTEN/PI3K/Akt pathway
por: Wang, Sai-Qi, et al.
Publicado: (2016)

Can molecular targeting the TNFα-ERK-ETS1-IL27Rα pathway keep us young and healthy by protecting HSCs from aging?
por: He, Yonghan, et al.
Publicado: (2020)

Ribosome Profiling Reveals Genome-wide Cellular Translational Regulation upon Heat Stress in Escherichia coli
por: Zhang, Yanqing, et al.
Publicado: (2017)

Vaginal microbiome analysis of healthy women during different periods of gestation
por: Li, Dan, et al.
Publicado: (2020)

Risk Factors Identification of Unsafe Acts in Deep Coal Mine Workers Based on Grounded Theory and HFACS
por: Yang, Li, et al.
Publicado: (2022)

Muscle Fatigue-Alleviating Effects of a Prescription Composed of Polygonati Rhizoma and Notoginseng Radix et Rhizoma
por: Yang, Ya-Qin, et al.
Publicado: (2020)

Decreased FOXF2 mRNA Expression Indicates Early-Onset Metastasis and Poor Prognosis for Breast Cancer Patients with Histological Grade II Tumor
por: Kong, Peng-Zhou, et al.
Publicado: (2013)

A Normalization-Free and Nonparametric Method Sharpens Large-Scale Transcriptome Analysis and Reveals Common Gene Alteration Patterns in Cancers
por: Li, Qi-Gang, et al.
Publicado: (2017)

Coordination of Ribosomal Protein and Ribosomal RNA Gene Expression in Response to TOR Signaling
por: Xiao, LiJuan, et al.
Publicado: (2009)

Correction to: Longitudinal transcriptomic characterization of viral genes in HSV-1 infected tree shrew trigeminal ganglia
por: Wang, Erlin, et al.
Publicado: (2020)

Longitudinal transcriptomic characterization of viral genes in HSV-1 infected tree shrew trigeminal ganglia
por: Wang, Erlin, et al.
Publicado: (2020)

The trinity of ribosome-associated quality control and stress signaling for proteostasis and neuronal physiology
por: Park, Jumin, et al.
Publicado: (2021)

Negative Pressure Wound Therapy Decreases Mortality in a Murine Model of Burn-Wound Sepsis Involving Pseudomonas aeruginosa Infection
por: Liu, Yang, et al.
Publicado: (2014)

Reanalysis of ribosome profiling datasets reveals a function of rocaglamide A in perturbing the dynamics of translation elongation via eIF4A
por: Li, Fajin, et al.
Publicado: (2023)

An updated meta-analysis of the prognostic value of decreased E-cadherin expression in ovarian cancer
por: Yu, LiLi, et al.
Publicado: (2017)

Ribosome-associated chaperones act as proteostasis sentinels
por: Kirstein-Miles, Janine, et al.
Publicado: (2013)

Construction of Escherichia coli Mutant with Decreased Endotoxic Activity by Modifying Lipid A Structure
por: Liu, Qiong, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_qi27iju2eo60s5ljrjae9cogh5