Mechanical tension mobilizes Lgr6(+) epidermal stem cells to drive skin growth

Uniquely among mammalian organs, skin is capable of marked size change in adults, yet the mechanisms underlying this notable capacity are unclear. Here, we use a system of controlled tissue expansion in mice to uncover cellular and molecular determinants of skin growth. Through machine learning–guid...

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Detalles Bibliográficos
Autores principales: Xue, Yingchao, Lyu, Chenyi, Taylor, Ainsley, Van Ee, Amy, Kiemen, Ashley, Choi, YoungGeun, Khavanian, Nima, Henn, Dominic, Lee, Chaewon, Hwang, Lisa, Wier, Eric, Wang, Saifeng, Lee, Sam, Li, Ang, Kirby, Charles, Wang, Gaofeng, Wu, Pei-Hsun, Wirtz, Denis, Garza, Luis A., Reddy, Sashank K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045722/
https://www.ncbi.nlm.nih.gov/pubmed/35476447
http://dx.doi.org/10.1126/sciadv.abl8698

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