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Development and characterization of new tools for detecting poly(ADP-ribose) in vitro and in vivo

ADP-ribosylation (ADPRylation) is a reversible post-translation modification resulting in the covalent attachment of ADP-ribose (ADPR) moieties on substrate proteins. Naturally occurring protein motifs and domains, including WWEs, PBZs, and macrodomains, act as ‘readers’ for protein-linked ADPR. Alt...

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Detalles Bibliográficos
Autores principales:	Challa, Sridevi, Ryu, Keun W, Whitaker, Amy L, Abshier, Jonathan C, Camacho, Cristel V, Kraus, W Lee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2022
Materias:	Biochemistry and Chemical Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045816/ https://www.ncbi.nlm.nih.gov/pubmed/35476036 http://dx.doi.org/10.7554/eLife.72464

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