Cargando…
Probable cross-corridor transmission of SARS-CoV-2 due to cross airflows and its control
A COVID-19 outbreak occurred in May 2020 in a public housing building in Hong Kong – Luk Chuen House, located in Lek Yuen Estate. The horizontal cluster linked to the index case’ flat (flat 812) remains to be explained. Computational fluid dynamics simulations were conducted to obtain the wind-press...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045881/ https://www.ncbi.nlm.nih.gov/pubmed/35502296 http://dx.doi.org/10.1016/j.buildenv.2022.109137 |
_version_ | 1784695414872604672 |
---|---|
author | Cheng, Pan Chen, Wenzhao Xiao, Shenglan Xue, Fan Wang, Qun Chan, Pak Wai You, Ruoyu Lin, Zhang Niu, Jianlei Li, Yuguo |
author_facet | Cheng, Pan Chen, Wenzhao Xiao, Shenglan Xue, Fan Wang, Qun Chan, Pak Wai You, Ruoyu Lin, Zhang Niu, Jianlei Li, Yuguo |
author_sort | Cheng, Pan |
collection | PubMed |
description | A COVID-19 outbreak occurred in May 2020 in a public housing building in Hong Kong – Luk Chuen House, located in Lek Yuen Estate. The horizontal cluster linked to the index case’ flat (flat 812) remains to be explained. Computational fluid dynamics simulations were conducted to obtain the wind-pressure coefficients of each external opening on the eighth floor of the building. The data were then used in a multi-zone airflow model to estimate the airflow rate and aerosol concentration in the flats and corridors on that floor. Apart from flat 812 and corridors, the virus-laden aerosol concentrations in flats 811, 813, 815, 817 and 819 (opposite to flat 812, across the corridor) were the highest on the eighth floor. When the doors of flats 813 and 817 were opened by 20%, the hourly-averaged aerosol concentrations in these two flats were at least four times as high as those in flats 811, 815 and 819 during the index case's home hours or the suspected exposure period of secondary cases. Thus, the flats across the corridor that were immediately downstream from flat 812 were at the highest exposure risk under a prevailing easterly wind, especially when their doors or windows that connected to the corridor were open. Given that the floorplan and dimension of Luk Chuen House are similar to those of many hotels, our findings provide a probable explanation for COVID-19 outbreaks in quarantine hotels. Positive pressure and sufficient ventilation in the corridor would help to minimise such cross-corridor infections. |
format | Online Article Text |
id | pubmed-9045881 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-90458812022-04-28 Probable cross-corridor transmission of SARS-CoV-2 due to cross airflows and its control Cheng, Pan Chen, Wenzhao Xiao, Shenglan Xue, Fan Wang, Qun Chan, Pak Wai You, Ruoyu Lin, Zhang Niu, Jianlei Li, Yuguo Build Environ Article A COVID-19 outbreak occurred in May 2020 in a public housing building in Hong Kong – Luk Chuen House, located in Lek Yuen Estate. The horizontal cluster linked to the index case’ flat (flat 812) remains to be explained. Computational fluid dynamics simulations were conducted to obtain the wind-pressure coefficients of each external opening on the eighth floor of the building. The data were then used in a multi-zone airflow model to estimate the airflow rate and aerosol concentration in the flats and corridors on that floor. Apart from flat 812 and corridors, the virus-laden aerosol concentrations in flats 811, 813, 815, 817 and 819 (opposite to flat 812, across the corridor) were the highest on the eighth floor. When the doors of flats 813 and 817 were opened by 20%, the hourly-averaged aerosol concentrations in these two flats were at least four times as high as those in flats 811, 815 and 819 during the index case's home hours or the suspected exposure period of secondary cases. Thus, the flats across the corridor that were immediately downstream from flat 812 were at the highest exposure risk under a prevailing easterly wind, especially when their doors or windows that connected to the corridor were open. Given that the floorplan and dimension of Luk Chuen House are similar to those of many hotels, our findings provide a probable explanation for COVID-19 outbreaks in quarantine hotels. Positive pressure and sufficient ventilation in the corridor would help to minimise such cross-corridor infections. Elsevier Ltd. 2022-06-15 2022-04-28 /pmc/articles/PMC9045881/ /pubmed/35502296 http://dx.doi.org/10.1016/j.buildenv.2022.109137 Text en © 2022 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Cheng, Pan Chen, Wenzhao Xiao, Shenglan Xue, Fan Wang, Qun Chan, Pak Wai You, Ruoyu Lin, Zhang Niu, Jianlei Li, Yuguo Probable cross-corridor transmission of SARS-CoV-2 due to cross airflows and its control |
title | Probable cross-corridor transmission of SARS-CoV-2 due to cross airflows and its control |
title_full | Probable cross-corridor transmission of SARS-CoV-2 due to cross airflows and its control |
title_fullStr | Probable cross-corridor transmission of SARS-CoV-2 due to cross airflows and its control |
title_full_unstemmed | Probable cross-corridor transmission of SARS-CoV-2 due to cross airflows and its control |
title_short | Probable cross-corridor transmission of SARS-CoV-2 due to cross airflows and its control |
title_sort | probable cross-corridor transmission of sars-cov-2 due to cross airflows and its control |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045881/ https://www.ncbi.nlm.nih.gov/pubmed/35502296 http://dx.doi.org/10.1016/j.buildenv.2022.109137 |
work_keys_str_mv | AT chengpan probablecrosscorridortransmissionofsarscov2duetocrossairflowsanditscontrol AT chenwenzhao probablecrosscorridortransmissionofsarscov2duetocrossairflowsanditscontrol AT xiaoshenglan probablecrosscorridortransmissionofsarscov2duetocrossairflowsanditscontrol AT xuefan probablecrosscorridortransmissionofsarscov2duetocrossairflowsanditscontrol AT wangqun probablecrosscorridortransmissionofsarscov2duetocrossairflowsanditscontrol AT chanpakwai probablecrosscorridortransmissionofsarscov2duetocrossairflowsanditscontrol AT youruoyu probablecrosscorridortransmissionofsarscov2duetocrossairflowsanditscontrol AT linzhang probablecrosscorridortransmissionofsarscov2duetocrossairflowsanditscontrol AT niujianlei probablecrosscorridortransmissionofsarscov2duetocrossairflowsanditscontrol AT liyuguo probablecrosscorridortransmissionofsarscov2duetocrossairflowsanditscontrol |