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Probable cross-corridor transmission of SARS-CoV-2 due to cross airflows and its control

A COVID-19 outbreak occurred in May 2020 in a public housing building in Hong Kong – Luk Chuen House, located in Lek Yuen Estate. The horizontal cluster linked to the index case’ flat (flat 812) remains to be explained. Computational fluid dynamics simulations were conducted to obtain the wind-press...

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Autores principales: Cheng, Pan, Chen, Wenzhao, Xiao, Shenglan, Xue, Fan, Wang, Qun, Chan, Pak Wai, You, Ruoyu, Lin, Zhang, Niu, Jianlei, Li, Yuguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045881/
https://www.ncbi.nlm.nih.gov/pubmed/35502296
http://dx.doi.org/10.1016/j.buildenv.2022.109137
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author Cheng, Pan
Chen, Wenzhao
Xiao, Shenglan
Xue, Fan
Wang, Qun
Chan, Pak Wai
You, Ruoyu
Lin, Zhang
Niu, Jianlei
Li, Yuguo
author_facet Cheng, Pan
Chen, Wenzhao
Xiao, Shenglan
Xue, Fan
Wang, Qun
Chan, Pak Wai
You, Ruoyu
Lin, Zhang
Niu, Jianlei
Li, Yuguo
author_sort Cheng, Pan
collection PubMed
description A COVID-19 outbreak occurred in May 2020 in a public housing building in Hong Kong – Luk Chuen House, located in Lek Yuen Estate. The horizontal cluster linked to the index case’ flat (flat 812) remains to be explained. Computational fluid dynamics simulations were conducted to obtain the wind-pressure coefficients of each external opening on the eighth floor of the building. The data were then used in a multi-zone airflow model to estimate the airflow rate and aerosol concentration in the flats and corridors on that floor. Apart from flat 812 and corridors, the virus-laden aerosol concentrations in flats 811, 813, 815, 817 and 819 (opposite to flat 812, across the corridor) were the highest on the eighth floor. When the doors of flats 813 and 817 were opened by 20%, the hourly-averaged aerosol concentrations in these two flats were at least four times as high as those in flats 811, 815 and 819 during the index case's home hours or the suspected exposure period of secondary cases. Thus, the flats across the corridor that were immediately downstream from flat 812 were at the highest exposure risk under a prevailing easterly wind, especially when their doors or windows that connected to the corridor were open. Given that the floorplan and dimension of Luk Chuen House are similar to those of many hotels, our findings provide a probable explanation for COVID-19 outbreaks in quarantine hotels. Positive pressure and sufficient ventilation in the corridor would help to minimise such cross-corridor infections.
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spelling pubmed-90458812022-04-28 Probable cross-corridor transmission of SARS-CoV-2 due to cross airflows and its control Cheng, Pan Chen, Wenzhao Xiao, Shenglan Xue, Fan Wang, Qun Chan, Pak Wai You, Ruoyu Lin, Zhang Niu, Jianlei Li, Yuguo Build Environ Article A COVID-19 outbreak occurred in May 2020 in a public housing building in Hong Kong – Luk Chuen House, located in Lek Yuen Estate. The horizontal cluster linked to the index case’ flat (flat 812) remains to be explained. Computational fluid dynamics simulations were conducted to obtain the wind-pressure coefficients of each external opening on the eighth floor of the building. The data were then used in a multi-zone airflow model to estimate the airflow rate and aerosol concentration in the flats and corridors on that floor. Apart from flat 812 and corridors, the virus-laden aerosol concentrations in flats 811, 813, 815, 817 and 819 (opposite to flat 812, across the corridor) were the highest on the eighth floor. When the doors of flats 813 and 817 were opened by 20%, the hourly-averaged aerosol concentrations in these two flats were at least four times as high as those in flats 811, 815 and 819 during the index case's home hours or the suspected exposure period of secondary cases. Thus, the flats across the corridor that were immediately downstream from flat 812 were at the highest exposure risk under a prevailing easterly wind, especially when their doors or windows that connected to the corridor were open. Given that the floorplan and dimension of Luk Chuen House are similar to those of many hotels, our findings provide a probable explanation for COVID-19 outbreaks in quarantine hotels. Positive pressure and sufficient ventilation in the corridor would help to minimise such cross-corridor infections. Elsevier Ltd. 2022-06-15 2022-04-28 /pmc/articles/PMC9045881/ /pubmed/35502296 http://dx.doi.org/10.1016/j.buildenv.2022.109137 Text en © 2022 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Cheng, Pan
Chen, Wenzhao
Xiao, Shenglan
Xue, Fan
Wang, Qun
Chan, Pak Wai
You, Ruoyu
Lin, Zhang
Niu, Jianlei
Li, Yuguo
Probable cross-corridor transmission of SARS-CoV-2 due to cross airflows and its control
title Probable cross-corridor transmission of SARS-CoV-2 due to cross airflows and its control
title_full Probable cross-corridor transmission of SARS-CoV-2 due to cross airflows and its control
title_fullStr Probable cross-corridor transmission of SARS-CoV-2 due to cross airflows and its control
title_full_unstemmed Probable cross-corridor transmission of SARS-CoV-2 due to cross airflows and its control
title_short Probable cross-corridor transmission of SARS-CoV-2 due to cross airflows and its control
title_sort probable cross-corridor transmission of sars-cov-2 due to cross airflows and its control
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045881/
https://www.ncbi.nlm.nih.gov/pubmed/35502296
http://dx.doi.org/10.1016/j.buildenv.2022.109137
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