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Histone Methyltransferase SETDB1 Promotes Immune Evasion in Colorectal Cancer via FOSB-Mediated Downregulation of MicroRNA-22 through BATF3/PD-L1 Pathway

Tumors may develop a variety of immune evasion mechanisms during the progression of colorectal cancer (CRC). Here, we intended to explore the mechanism of histone methyltransferase SETDB1 in immune evasion in CRC. The expression of SETDB1, microRNA-22 (miR-22), BATF3, PD-L1, and FOSB in CRC tissues...

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Detalles Bibliográficos
Autores principales:	Tian, Jiale, Wang, Weiwei, Zhu, Jichao, Zhuang, Yun, Qi, Chunrun, Cai, Zhengxin, Yan, Wenhui, Lu, Wenying, Shang, Anquan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045983/ https://www.ncbi.nlm.nih.gov/pubmed/35497876 http://dx.doi.org/10.1155/2022/4012920

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