Combination Treatment of Omega-3 Fatty Acids and Vitamin C Exhibited Promising Therapeutic Effect against Oxidative Impairment of the Liver in Methotrexate-Intoxicated Mice

Drug-induced liver injury (DILI) is the main cause of liver damage mediated by the excretion of toxic active drug metabolites. Omega-3 fatty acids and vitamin C have potent antioxidant, anti-inflammatory, and antiapoptotic effects that could offer protection against oxidative stress and liver damage...

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Detalles Bibliográficos
Autores principales: Alorabi, Mohammed, Mohammed, Doha Saad, Mostafa-Hedeab, Gomaa, El-Sherbeni, Suzy A., Negm, Walaa A., Mohammed, Ali Ismail A., Al-kuraishy, Hayder M., Nasreldin, Nani, Alotaibi, Saqer S., Lawal, Bashir, Batiha, Gaber El-Saber, Conte-Junior, Carlos Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045995/
https://www.ncbi.nlm.nih.gov/pubmed/35496049
http://dx.doi.org/10.1155/2022/4122166

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