Screening for modulators of the cellular composition of gut epithelia via organoid models of intestinal stem cell differentiation

The cellular composition of barrier epithelia is essential to organismal homoeostasis. In particular, within the small intestine, adult stem cells establish tissue cellularity, and may provide a means to control the abundance and quality of specialized epithelial cells. Yet, methods for the identifi...

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Detalles Bibliográficos
Autores principales: Mead, Benjamin E., Hattori, Kazuki, Levy, Lauren, Imada, Shinya, Goto, Norihiro, Vukovic, Marko, Sze, Daphne, Kummerlowe, Conner, Matute, Juan D., Duan, Jinzhi, Langer, Robert, Blumberg, Richard S., Ordovas-Montanes, Jose, Yilmaz, Ömer H., Karp, Jeffrey M., Shalek, Alex K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046079/
https://www.ncbi.nlm.nih.gov/pubmed/35314801
http://dx.doi.org/10.1038/s41551-022-00863-9

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