Perivascular tenascin C triggers sequential activation of macrophages and endothelial cells to generate a pro-metastatic vascular niche in the lungs

Disseminated cancer cells frequently lodge near vasculature in secondary organs. However, our understanding of the cellular crosstalk invoked at perivascular sites is still rudimentary. Here, we identify intercellular machinery governing formation of a pro-metastatic vascular niche during breast can...

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Detalles Bibliográficos
Autores principales: Hongu, Tsunaki, Pein, Maren, Insua-Rodríguez, Jacob, Gutjahr, Ewgenija, Mattavelli, Greta, Meier, Jasmin, Decker, Kristin, Descot, Arnaud, Bozza, Matthias, Harbottle, Richard, Trumpp, Andreas, Sinn, Hans-Peter, Riedel, Angela, Oskarsson, Thordur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046090/
https://www.ncbi.nlm.nih.gov/pubmed/35469015
http://dx.doi.org/10.1038/s43018-022-00353-6

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