Cargando…

Deprenyl reduces inflammation during acute SIV infection

In the era of antiretroviral therapy, inflammation is a central factor in numerous HIV-associated comorbidities, such as cardiovascular disease, cognitive impairment, and neuropsychiatric disorders. This highlights the value of developing therapeutics that both reduce HIV-associated inflammation and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Emanuel, K.M., Runner, K., Brodnik, Z.D., Morsey, B.M., Lamberty, B.G., Johnson, H.S., Acharya, A., Byrareddy, S.N., España, R.A., Fox, H.S., Gaskill, P.J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046124/ https://www.ncbi.nlm.nih.gov/pubmed/35494221 http://dx.doi.org/10.1016/j.isci.2022.104207

Ejemplares similares

Dopamine activates NF-κB and primes the NLRP3 inflammasome in primary human macrophages
por: Nolan, R.A., et al.
Publicado: (2019)

Morphine suppresses peripheral responses and transforms brain myeloid gene expression to favor neuropathogenesis in SIV infection
por: Fox, Howard S., et al.
Publicado: (2022)

Methamphetamine Increases the Proportion of SIV-Infected Microglia/Macrophages, Alters Metabolic Pathways, and Elevates Cell Death Pathways: A Single-Cell Analysis
por: Niu, Meng, et al.
Publicado: (2020)

Antiretroviral therapy restores the homeostatic state of microglia in SIV‐infected rhesus macaques
por: Trease, Andrew J., et al.
Publicado: (2022)

MiR-21 in Extracellular Vesicles Leads to Neurotoxicity via TLR7 Signaling in SIV Neurological Disease
por: Yelamanchili, Sowmya V., et al.
Publicado: (2015)

Correction: MiR-21 in Extracellular Vesicles Leads to Neurotoxicity via TLR7 Signaling in SIV Neurological Disease
por: Yelamanchili, Sowmya V., et al.
Publicado: (2015)

Correction: MiR-21 in Extracellular Vesicles Leads to Neurotoxicity via TLR7 Signaling in SIV Neurological Disease
por: Yelamanchili, Sowmya V., et al.
Publicado: (2018)

Development and characterization of positively selected brain-adapted SIV
por: Gaskill, Peter J, et al.
Publicado: (2005)

EMSAM (deprenyl patch): how a promising antidepressant was underutilized
por: Asnis, Gregory M, et al.
Publicado: (2014)

Deprenyl Enhances the Teratogenicity of Hydroxyurea in Organogenesis Stage Mouse Embryos
por: Schlisser, Ava E., et al.
Publicado: (2013)

Maturation of protective immunity induced by SIVΔnef correlates with differential expression of transcription factors in SIV-specific CD8+ T cells
por: Billingsley, JM, et al.
Publicado: (2012)

Chronic Morphine Administration Differentially Modulates Viral Reservoirs in a Simian Immunodeficiency Virus SIVmac251-Infected Rhesus Macaque Model
por: Acharya, Arpan, et al.
Publicado: (2021)

Chronic Experimental Diabetes Accelerates Urinary Elimination of Deprenyl and its Metabolites
por: Adeghate, Ernest, et al.
Publicado: (2008)

EMSAM (deprenyl patch): how a promising antidepressant was underutilized [Corrigendum]
Publicado: (2014)

Differential Modulation of the Central and Peripheral Monoaminergic Neurochemicals by Deprenyl in Zebrafish Larvae
por: Bellot, Marina, et al.
Publicado: (2021)

Phenotypic changes in the brain of SIV-infected macaques exposed to methamphetamine parallel macrophage activation patterns induced by the common gamma-chain cytokine system
por: Bortell, Nikki, et al.
Publicado: (2015)

Monoamine oxidase inhibitors l-deprenyl and clorgyline protect nonmalignant human cells from ionising radiation and chemotherapy toxicity
por: Seymour, C B, et al.
Publicado: (2003)

Induction of miR-155 after Brain Injury Promotes Type 1 Interferon and has a Neuroprotective Effect
por: Harrison, Emily B., et al.
Publicado: (2017)

Expression of neurotrophic factor genes by human adipose stem cells post-induction by deprenyl
por: Amiri, Arezoo, et al.
Publicado: (2021)

Cryopreservation of microglia enables single-cell RNA sequencing with minimal effects on disease-related gene expression patterns
por: Morsey, Brenda, et al.
Publicado: (2021)

Diminished Peripheral CD29hi Cytotoxic CD4+ T Cells Are Associated With Deleterious Effects During SIV Infection
por: Olwenyi, Omalla A., et al.
Publicado: (2021)

Methamphetamine abuse affects gene expression in brain-derived microglia of SIV-infected macaques to enhance inflammation and promote virus targets
por: Najera, Julia A., et al.
Publicado: (2016)

An efficient preparation of labelling precursor of [(11)C]L-deprenyl-D(2) and automated radiosynthesis
por: Zirbesegger, Kevin, et al.
Publicado: (2017)

Protection against highly pathogenic SIV by BCG-SIV recombinant priming and attenuated replicating vaccinia-SIV recombinant boosting
por: Zhang, X, et al.
Publicado: (2012)

Retinoic Acid Improves the Recovery of Replication-Competent Virus from Latent SIV Infected Cells
por: Olwenyi, Omalla A., et al.
Publicado: (2020)

Pharmacological Modulation of Behaviour, Serotonin and Dopamine Levels in Daphnia magna Exposed to the Monoamine Oxidase Inhibitor Deprenyl
por: Bellot, Marina, et al.
Publicado: (2021)

Elevated [11C]-D-Deprenyl Uptake in Chronic Whiplash Associated Disorder Suggests Persistent Musculoskeletal Inflammation
por: Linnman, Clas, et al.
Publicado: (2011)

Test-retest reproducibility of [(11)C]-l-deprenyl-D(2) binding to MAO-B in the human brain
por: Arakawa, Ryosuke, et al.
Publicado: (2017)

Nef interferes with development of thymic T cell precursors: differential mechanisms in HIV and SIV
por: Meuwissen, PJ, et al.
Publicado: (2011)

A new scoring model for characterization of adnexal masses based on two-dimensional gray-scale and colour Doppler sonographic features
por: Abbas, A.M., et al.
Publicado: (2014)

2-Deprenyl-Rheediaxanthone B Isolated from Metaxya rostrata Induces Active Cell Death in Colorectal Tumor Cells
por: Kainz, Kerstin P., et al.
Publicado: (2013)

Production of [(11)C]Carbon Labelled Flumazenil and L-Deprenyl Using the iMiDEV™ Automated Microfluidic Radiosynthesizer
por: Mallapura, Hemantha, et al.
Publicado: (2022)

The evolutionary young miR-1290 favors mitotic exit and differentiation of human neural progenitors through altering the cell cycle proteins
por: Yelamanchili, S V, et al.
Publicado: (2014)

Myeloid sarcoma: An unusual and rare laryngeal presentation
por: Tan, S.N., et al.
Publicado: (2016)

Correction: 2-Deprenyl-Rheediaxanthone B Isolated from Metaxya rostrata Induces Active Cell Death in Colorectal Tumor Cells
por: Kainz, Kerstin P., et al.
Publicado: (2013)

Neuroprotective effect of L-deprenyl on the expression level of the Mst1 gene and inhibition of apoptosis in rat-model spinal cord injury
por: Abdanipour, Alireza, et al.
Publicado: (2022)

Traumatic brain injury increases levels of miR‐21 in extracellular vesicles: implications for neuroinflammation
por: Harrison, Emily B., et al.
Publicado: (2016)

Mechanistic basis of post-treatment control of SIV after anti-α4β7 antibody therapy
por: Wells, Chad R., et al.
Publicado: (2021)

(3)H-Deprenyl and (3)H-PIB autoradiography show different laminar distributions of astroglia and fibrillar β-amyloid in Alzheimer brain
por: Marutle, Amelia, et al.
Publicado: (2013)

Cortical laminar tau deposits and activated astrocytes in Alzheimer’s disease visualised by (3)H-THK5117 and (3)H-deprenyl autoradiography
por: Lemoine, Laetitia, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_9mejf310pala7dvqao83vo6og8