Erythropoietin Abrogates Post-Ischemic Activation of the NLRP3, NLRC4, and AIM2 Inflammasomes in Microglia/Macrophages in a TAK1-Dependent Manner

Inflammasomes are known to contribute to brain damage after acute ischemic stroke (AIS). TAK1 is predominantly expressed in microglial cells and can regulate the NLRP3 inflammasome, but its impact on other inflammasomes including NLRC4 and AIM2 after AIS remains elusive. EPO has been shown to reduce...

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Detalles Bibliográficos
Autores principales: Heinisch, Ole, Zeyen, Thomas, Goldmann, Tobias, Prinz, Marco, Huber, Michael, Jung, Jennifer, Arik, Eren, Habib, Shahin, Slowik, Alexander, Reich, Arno, Schulz, Jörg B., Habib, Pardes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046144/
https://www.ncbi.nlm.nih.gov/pubmed/34628598
http://dx.doi.org/10.1007/s12975-021-00948-8

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