Cargando…

A distinctive ligand recognition mechanism by the human vasoactive intestinal polypeptide receptor 2

Class B1 of G protein-coupled receptors (GPCRs) comprises 15 members activated by physiologically important peptide hormones. Among them, vasoactive intestinal polypeptide receptor 2 (VIP2R) is expressed in the central and peripheral nervous systems and involved in a number of pathophysiological con...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Yingna, Feng, Wenbo, Zhou, Qingtong, Liang, Anyi, Li, Jie, Dai, Antao, Zhao, Fenghui, Yan, Jiahui, Chen, Chuan-Wei, Li, Hao, Zhao, Li-Hua, Xia, Tian, Jiang, Yi, Xu, H. Eric, Yang, Dehua, Wang, Ming-Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046186/ https://www.ncbi.nlm.nih.gov/pubmed/35477937 http://dx.doi.org/10.1038/s41467-022-30041-z

Ejemplares similares

Structural insights into ligand recognition and subtype selectivity of the human melanocortin-3 and melanocortin-5 receptors
por: Feng, Wenbo, et al.
Publicado: (2023)

Structural insights into hormone recognition by the human glucose-dependent insulinotropic polypeptide receptor
por: Zhao, Fenghui, et al.
Publicado: (2021)

Molecular basis of signal transduction mediated by the human GIPR splice variants
por: Zhao, Fenghui, et al.
Publicado: (2023)

Ligand recognition mechanism of the human relaxin family peptide receptor 4 (RXFP4)
por: Chen, Yan, et al.
Publicado: (2023)

Development-Dependent Plasticity in Vasoactive Intestinal Polypeptide Neurons in the Infralimbic Cortex
por: Collins, Stuart A, et al.
Publicado: (2021)

Structural insights into ligand recognition and selectivity of somatostatin receptors
por: Zhao, Wenli, et al.
Publicado: (2022)

Vasoactive Intestinal Polypeptide Promotes Intestinal Barrier Homeostasis and Protection Against Colitis in Mice
por: Wu, Xiujuan, et al.
Publicado: (2015)

Molecular insights into differentiated ligand recognition of the human parathyroid hormone receptor 2
por: Wang, Xi, et al.
Publicado: (2021)

Vasoactive Intestinal Polypeptide-Immunoreactive Interneurons within Circuits of the Mouse Basolateral Amygdala
por: Rhomberg, Thomas, et al.
Publicado: (2018)

Vasoactive Intestinal Polypeptide (VIP) in the Intestinal Mucosal Nerve Fibers in Dogs with Inflammatory Bowel Disease
por: Rychlik, Andrzej, et al.
Publicado: (2020)

Structural analysis of the dual agonism at GLP-1R and GCGR
por: Li, Yang, et al.
Publicado: (2023)

Multimodal Treatment of Vasoactive Intestinal Polypeptide-producing Pancreatic Neuroendocrine Tumors with Liver Metastases
por: Iwasaki, Mari, et al.
Publicado: (2017)

Effect of Vasoactive Intestinal Polypeptide on Development of Migraine Headaches: A Randomized Clinical Trial
por: Pellesi, Lanfranco, et al.
Publicado: (2021)

Role of vasoactive intestinal peptide in osteoarthritis
por: Jiang, Wei, et al.
Publicado: (2016)

Donor plasmacytoid dendritic cells limit graft-versus-host disease through vasoactive intestinal polypeptide expression
por: Zhu, Jingru, et al.
Publicado: (2022)

Parvalbumin- and vasoactive intestinal polypeptide-expressing neocortical interneurons impose differential inhibition on Martinotti cells
por: Walker, F., et al.
Publicado: (2016)

Retinoprotective Effects of TAT-Bound Vasoactive Intestinal Peptide and Pituitary Adenylate Cyclase Activating Polypeptide
por: Atlasz, Tamas, et al.
Publicado: (2018)

Structural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors
por: Zhao, Fenghui, et al.
Publicado: (2022)

Vasoactive Intestinal Polypeptide in the Carotid Body—A History of Forty Years of Research. A Mini Review
por: Gonkowski, Slawomir
Publicado: (2020)

Vasoactive intestinal polypeptide plasma levels associated with affective symptoms and brain structure and function in healthy females
por: Simon, Rozalyn A., et al.
Publicado: (2021)

Correlation of Decreased Serum Pituitary Adenylate Cyclase-Activating Polypeptide and Vasoactive Intestinal Peptide Levels With Non-motor Symptoms in Patients With Parkinson’s Disease
por: Hu, Shiyu, et al.
Publicado: (2021)

Discovery of Novel Allosteric Modulators Targeting an Extra-Helical Binding Site of GLP-1R Using Structure- and Ligand-Based Virtual Screening
por: Zhou, Qingtong, et al.
Publicado: (2021)

Bombesin-Like, Substance P and Vasoactive Intestinal Polypeptide Receptors in Fetal Cortical Homografts to Host Cortex and Spinal Cord
por: Moody, Terry W., et al.
Publicado: (1989)

Protective Effects of Pituitary Adenylate Cyclase-Activating Polypeptide and Vasoactive Intestinal Peptide Against Cognitive Decline in Neurodegenerative Diseases
por: Solés-Tarrés, Irene, et al.
Publicado: (2020)

Pancreatic tumor with hepatic metastases secreting vasoactive intestinal polypeptide: Treatment options and long-term follow-up results
por: Sözen, Mehmet, et al.
Publicado: (2023)

Ligand recognition and G-protein coupling selectivity of cholecystokinin A receptor
por: Liu, Qiufeng, et al.
Publicado: (2021)

Therapeutic effect of vasoactive intestinal peptide on form-deprived amblyopic kittens
por: Li, Bo, et al.
Publicado: (2019)

The Impact of T-2 Toxin on Vasoactive Intestinal Polypeptide-Like Immunoreactive (VIP-LI) Nerve Structures in the Wall of the Porcine Stomach and Duodenum
por: Makowska, Krystyna, et al.
Publicado: (2018)

Loss of arginine vasopressin- and vasoactive intestinal polypeptide-containing neurons and glial cells in the suprachiasmatic nucleus of individuals with type 2 diabetes
por: Hogenboom, Rick, et al.
Publicado: (2019)

FRI277 Temporal Coordination Of Female Reproductive Axis Activity By Vasoactive Intestinal Polypeptide (VIP) Expressing Cells In The Suprachiasmatic Nucleus
por: Phumsatitpong, Chayarndorn, et al.
Publicado: (2023)

A Unique Presentation and Clinical Course of a Pancreatic Vasoactive Intestinal Polypeptide Secreting Tumor in a 68-year-old Male
por: Jagdish, Balaji R., et al.
Publicado: (2020)

A microcircuit model involving parvalbumin, somatostatin, and vasoactive intestinal polypeptide inhibitory interneurons for the modulation of neuronal oscillation during visual processing
por: Wagatsuma, Nobuhiko, et al.
Publicado: (2022)

Structural basis of peptidomimetic agonism revealed by small-molecule GLP-1R agonists Boc5 and WB4-24
por: Cong, Zhaotong, et al.
Publicado: (2022)

The effects of vasoactive intestinal peptide on RANKL-induced osteoclast formation
por: Qu, Hongyi, et al.
Publicado: (2021)

Localization of Vasoactive Intestinal Polypeptide Receptor 1 (VPAC1) in Hypothalamic Neuroendocrine Oxytocin Neurons; A Potential Role in Circadian Prolactin Secretion
por: Stangerup, Ida, et al.
Publicado: (2020)

Editorial: Novel Therapeutic Potential for Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP), Vasoactive Intestinal Peptide (VIP) and Related Peptides in Cognition Deficits
por: Ciranna, Lucia, et al.
Publicado: (2021)

Vasoactive intestinal peptide secreting tumour: An overview
por: Una Cidon, Esther
Publicado: (2022)

Gut-Sourced Vasoactive Intestinal Polypeptide Induced by the Activation of α7 Nicotinic Acetylcholine Receptor Substantially Contributes to the Anti-inflammatory Effect of Sinomenine in Collagen-Induced Arthritis
por: Yue, MengFan, et al.
Publicado: (2018)

Cryo-EM structures of cancer-specific helical and kinase domain mutations of PI3Kα
por: Liu, Xiao, et al.
Publicado: (2022)

Recombinant expressed vasoactive intestinal peptide analogue ameliorates TNBS-induced colitis in rats
por: Xu, Chun-Lan, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_mhcummothbtr7bsvjaeovrqv56