Autophagy-Related Activation of Hepatic Stellate Cells Reduces Cellular miR-29a by Promoting Its Vesicular Secretion

BACKGROUND & AIMS: Liver fibrosis arises from long-term chronic liver injury, accompanied by an accelerated wound healing response with interstitial accumulation of extracellular matrix (ECM). Activated hepatic stellate cells (HSC) are the main source for ECM production. MicroRNA29a (miR-29a) is...

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Detalles Bibliográficos
Autores principales: Yu, Xiaojie, Elfimova, Natalia, Müller, Marion, Bachurski, Daniel, Koitzsch, Ulrike, Drebber, Uta, Mahabir, Esther, Hansen, Hinrich P., Friedman, Scott L., Klein, Sabine, Dienes, Hans Peter, Hösel, Marianna, Buettner, Reinhard, Trebicka, Jonel, Kondylis, Vangelis, Mannaerts, Inge, Odenthal, Margarete
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046234/
https://www.ncbi.nlm.nih.gov/pubmed/35219894
http://dx.doi.org/10.1016/j.jcmgh.2022.02.013

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