Deconvolution of the hematopoietic stem cell microenvironment reveals a high degree of specialization and conservation

Understanding the regulation of normal and malignant human hematopoiesis requires comprehensive cell atlas of the hematopoietic stem cell (HSC) regulatory microenvironment. Here, we develop a tailored bioinformatic pipeline to integrate public and proprietary single-cell RNA sequencing (scRNA-seq) d...

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Detalles Bibliográficos
Autores principales: Ye, Jin, Calvo, Isabel A., Cenzano, Itziar, Vilas, Amaia, Martinez-de-Morentin, Xabier, Lasaga, Miren, Alignani, Diego, Paiva, Bruno, Viñado, Ana C., San Martin-Uriz, Patxi, Romero, Juan P., Quilez Agreda, Delia, Miñana Barrios, Marta, Sancho-González, Ignacio, Todisco, Gabriele, Malcovati, Luca, Planell, Nuria, Saez, Borja, Tegner, Jesper N., Prosper, Felipe, Gomez-Cabrero, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046238/
https://www.ncbi.nlm.nih.gov/pubmed/35494238
http://dx.doi.org/10.1016/j.isci.2022.104225

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