Differential expression of an endogenous retroviral element [HERV-K(HML-6)] is associated with reduced survival in glioblastoma patients

Comprising approximately 8% of our genome, Human Endogenous RetroViruses (HERVs) represent a class of germline retroviral infections that are regulated through epigenetic modifications. In cancer cells, which often have epigenetic dysregulation, HERVs have been implicated as potential oncogenic driv...

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Detalles Bibliográficos
Autores principales: Shah, Ashish H., Govindarajan, Vaidya, Doucet-O’Hare, Tara T., Rivas, Sarah, Ampie, Leo, DeMarino, Catherine, Banasavadi-Siddegowda, Yeshavanth Kumar, Zhang, Yong, Johnson, Kory R., Almsned, Fahad, Gilbert, Mark R., Heiss, John D., Nath, Avindra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046263/
https://www.ncbi.nlm.nih.gov/pubmed/35477752
http://dx.doi.org/10.1038/s41598-022-10914-5

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