EWSR1-ATF1 dependent 3D connectivity regulates oncogenic and differentiation programs in Clear Cell Sarcoma

Oncogenic fusion proteins generated by chromosomal translocations play major roles in cancer. Among them, fusions between EWSR1 and transcription factors generate oncogenes with powerful chromatin regulatory activities, capable of establishing complex gene expression programs in permissive precursor...

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Detalles Bibliográficos
Autores principales: Möller, Emely, Praz, Viviane, Rajendran, Sanalkumar, Dong, Rui, Cauderay, Alexandra, Xing, Yu-Hang, Lee, Lukuo, Fusco, Carlo, Broye, Liliane C., Cironi, Luisa, Iyer, Sowmya, Rengarajan, Shruthi, Awad, Mary E., Naigles, Beverly, Letovanec, Igor, Ormas, Nicola, Finzi, Giovanna, La Rosa, Stefano, Sessa, Fausto, Chebib, Ivan, Petur Nielsen, G., Digklia, Antonia, Spentzos, Dimitrios, Cote, Gregory M., Choy, Edwin, Aryee, Martin, Stamenkovic, Ivan, Boulay, Gaylor, Rivera, Miguel N., Riggi, Nicolò
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046276/
https://www.ncbi.nlm.nih.gov/pubmed/35477713
http://dx.doi.org/10.1038/s41467-022-29910-4

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