Cargando…

High altitude is associated with pTau deposition, neuroinflammation, and myelin loss

Mammals are able to adapt to high altitude (HA) if appropriate acclimation occurs. However, specific occupations (professional climbers, pilots, astronauts and other) can be exposed to HA without acclimation and be at a higher risk of brain consequences. In particular, US Air Force U2-pilots have be...

Descripción completa

Detalles Bibliográficos
Autores principales:	Iacono, Diego, Murphy, Erin K., Sherman, Paul M., Chapapas, Holly, Cerqueira, Bianca, Christensen, Christine, Perl, Daniel P., Sladky, John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046305/ https://www.ncbi.nlm.nih.gov/pubmed/35477957 http://dx.doi.org/10.1038/s41598-022-10881-x

Ejemplares similares

Reduction of pTau and APP levels in mammalian brain after low-dose radiation
por: Iacono, Diego, et al.
Publicado: (2021)

Comparing tau status determined via plasma pTau181, pTau231 and [(18)F]MK6240 tau-PET
por: Tissot, Cécile, et al.
Publicado: (2022)

Characterization of Novel CSF Tau and ptau Biomarkers for Alzheimer’s Disease
por: Meredith Jr., Jere E., et al.
Publicado: (2013)

Cortical microstructural associations with CSF amyloid and pTau
por: Nir, Talia M., et al.
Publicado: (2023)

Plasma pTau181 as a biomarker for Alzheimer's disease
por: Meng, Jie, et al.
Publicado: (2020)

Accumulation of pTau231 at the Postsynaptic Density in Early Alzheimer’s Disease
por: Lilek, Jaclyn, et al.
Publicado: (2023)

Potential association between frailty and pTau in community-dwelling older adults
por: Zhou, Lixing, et al.
Publicado: (2022)

Double Blast Wave Primary Effect on Synaptic, Glymphatic, Myelin, Neuronal and Neurovascular Markers
por: Iacono, Diego, et al.
Publicado: (2023)

Diagnostic accuracy of the plasma ALZpath pTau217 immunoassay to identify Alzheimer’s disease pathology
por: Ashton, Nicholas J., et al.
Publicado: (2023)

Plasma pTau181 predicts cortical brain atrophy in aging and Alzheimer’s disease
por: Tissot, Cécile, et al.
Publicado: (2021)

Cerebrospinal fluid tau and ptau(181) increase with cortical amyloid deposition in cognitively normal individuals: Implications for future clinical trials of Alzheimer's disease
por: Fagan, Anne M, et al.
Publicado: (2009)

A Head-to-Head Comparison Between Plasma pTau181 and Tau PET Along the Alzheimer’s Disease Continuum
por: Coomans, Emma M., et al.
Publicado: (2023)

Low-dose brain radiation: lowering hyperphosphorylated-tau without increasing DNA damage or oncogenic activation
por: Iacono, Diego, et al.
Publicado: (2023)

A Longitudinal Study of Plasma pTau181 in Mild Cognitive Impairment with Lewy Bodies and Alzheimer's Disease
por: Thomas, Alan J., et al.
Publicado: (2022)

Amyloid-β levels and cognitive trajectories in non-demented pTau181-positive subjects without amyloidopathy
por: Oberstein, Timo Jan, et al.
Publicado: (2022)

ApoER2-Dab1 disruption as the origin of pTau-related neurodegeneration in sporadic Alzheimer’s disease
por: Ramsden, Christopher E., et al.
Publicado: (2023)

ApoER2-Dab1 disruption as the origin of pTau-related neurodegeneration in sporadic Alzheimer’s disease
por: Ramsden, Christopher E, et al.
Publicado: (2023)

Chronic Exposure to High Altitude: Synaptic, Astroglial and Memory Changes
por: Sharma, Rupali, et al.
Publicado: (2019)

Crystal structure of ultra-humanized anti-pTau Fab reveals how germline substitutions humanize CDRs without loss of binding’
por: Brinth, Alette R., et al.
Publicado: (2022)

Normalization of CSF pTau measurement by Aβ(40) improves its performance as a biomarker of Alzheimer’s disease
por: Guo, Tengfei, et al.
Publicado: (2020)

Modeling Alzheimer’s disease related phenotypes in the Ts65Dn mouse: impact of age on Aβ, Tau, pTau, NfL, and behavior
por: Overk, Cassia, et al.
Publicado: (2023)

The Expression of Cellular Prion Protein, PrPC, Favors pTau Propagation and Blocks NMDAR Signaling in Primary Cortical Neurons
por: Rivas-Santisteban, Rafael, et al.
Publicado: (2023)

Predicting clinical decline and conversion to Alzheimer’s disease or dementia using novel Elecsys Aβ(1–42), pTau and tTau CSF immunoassays
por: Blennow, Kaj, et al.
Publicado: (2019)

Repetitive mild TBI causes pTau aggregation in nigra without altering preexisting fibril induced Parkinson’s-like pathology burden
por: Delic, Vedad, et al.
Publicado: (2022)

Agomelatine Prevents Amyloid Plaque Deposition, Tau Phosphorylation, and Neuroinflammation in APP/PS1 Mice
por: Yang, Xiao-bo, et al.
Publicado: (2022)

Pulmonary Embolism Masquerading as High Altitude Pulmonary Edema at High Altitude
por: Pandey, Prativa, et al.
Publicado: (2016)

The relationships between neuroinflammation, beta-amyloid and tau deposition in Alzheimer’s disease: a longitudinal PET study
por: Ismail, Rola, et al.
Publicado: (2020)

Apolipoprotein E promoter genotypes are not associated with white matter hyperintensity development in high-altitude careers
por: Chapleau, Richard R., et al.
Publicado: (2019)

DNA-templated synthesis of PtAu bimetallic nanoparticle/graphene nanocomposites and their application in glucose biosensor
por: Leng, Jing, et al.
Publicado: (2014)

Resistance and resilience to Alzheimer’s disease pathology are associated with reduced cortical pTau and absence of limbic-predominant age-related TDP-43 encephalopathy in a community-based cohort
por: Latimer, Caitlin S., et al.
Publicado: (2019)

Reduction of AMPA receptor activity on mature oligodendrocytes attenuates loss of myelinated axons in autoimmune neuroinflammation
por: Evonuk, Kirsten S., et al.
Publicado: (2020)

Characterization of Au and Bimetallic PtAu Nanoparticles on PDDA-Graphene Sheets as Electrocatalysts for Formic Acid Oxidation
por: Yung, Tung-Yuan, et al.
Publicado: (2015)

Counteranion-induced structural isomerization of phosphine-protected PdAu(8) and PtAu(8) clusters
por: Fujiki, Yu, et al.
Publicado: (2023)

Evaluating apolipoprotein E genotype status and neuroprotective effects against white matter hyperintensity development in high-altitude careers
por: Chapleau, Richard R., et al.
Publicado: (2018)

LMP2 deficiency causes abnormal metabolism, oxidative stress, neuroinflammation, myelin loss and neurobehavioral dysfunctions
por: Chen, Xingyong, et al.
Publicado: (2023)

CD36-mediated uptake of myelin debris by macrophages and microglia reduces neuroinflammation
por: Grajchen, Elien, et al.
Publicado: (2020)

Myelin Disruption, Neuroinflammation, and Oxidative Stress Induced by Sulfite in the Striatum of Rats Are Mitigated by the pan-PPAR agonist Bezafibrate
por: Glänzel, Nícolas Manzke, et al.
Publicado: (2023)

A molecule-like PtAu(24)(SC(6)H(13))(18) nanocluster as an electrocatalyst for hydrogen production
por: Kwak, Kyuju, et al.
Publicado: (2017)

Correlation of pyroglutamate amyloid β and ptau Ser202/Thr205 levels in Alzheimer’s disease and related murine models
por: Neddens, Joerg, et al.
Publicado: (2020)

Ultrasmall PtAu(2) nanoclusters activate endogenous anti-inflammatory and anti-oxidative systems to prevent inflammatory osteolysis
por: Chen, Xuzhuo, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_vf242mdk0gr2t0vje51qd92tjt