The timing of differentiation and potency of CD8 effector function is set by RNA binding proteins

CD8(+) T cell differentiation into effector cells is initiated early after antigen encounter by signals from the T cell antigen receptor and costimulatory molecules. The molecular mechanisms that establish the timing and rate of differentiation however are not defined. Here we show that the RNA bind...

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Detalles Bibliográficos
Autores principales: Petkau, Georg, Mitchell, Twm J., Chakraborty, Krishnendu, Bell, Sarah E., D´Angeli, Vanessa, Matheson, Louise, Turner, David J., Saveliev, Alexander, Gizlenci, Ozge, Salerno, Fiamma, Katsikis, Peter D., Turner, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046422/
https://www.ncbi.nlm.nih.gov/pubmed/35477960
http://dx.doi.org/10.1038/s41467-022-29979-x

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