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Phospholipase A(2)-based probes to study vesicle trafficking

Vesicle exo- and endocytosis mediate important biological functions, including synaptic transmission. In this issue of Cell Reports Methods, Seong J. An et al. found that the fluorescently tagged C2 domain of phospholipase A(2) binds to membrane phosphatidylcholine and thus labels vesicle membrane,...

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Detalles Bibliográficos
Autores principales: Wang, Xin, Sun, Min, Chan, Chung Yu, Wu, Ling-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046444/
https://www.ncbi.nlm.nih.gov/pubmed/35497501
http://dx.doi.org/10.1016/j.crmeth.2022.100206
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author Wang, Xin
Sun, Min
Chan, Chung Yu
Wu, Ling-Gang
author_facet Wang, Xin
Sun, Min
Chan, Chung Yu
Wu, Ling-Gang
author_sort Wang, Xin
collection PubMed
description Vesicle exo- and endocytosis mediate important biological functions, including synaptic transmission. In this issue of Cell Reports Methods, Seong J. An et al. found that the fluorescently tagged C2 domain of phospholipase A(2) binds to membrane phosphatidylcholine and thus labels vesicle membrane, allowing for super-resolution and electron microscopic visualization of vesicle trafficking.
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spelling pubmed-90464442022-04-29 Phospholipase A(2)-based probes to study vesicle trafficking Wang, Xin Sun, Min Chan, Chung Yu Wu, Ling-Gang Cell Rep Methods Preview Vesicle exo- and endocytosis mediate important biological functions, including synaptic transmission. In this issue of Cell Reports Methods, Seong J. An et al. found that the fluorescently tagged C2 domain of phospholipase A(2) binds to membrane phosphatidylcholine and thus labels vesicle membrane, allowing for super-resolution and electron microscopic visualization of vesicle trafficking. Elsevier 2022-04-25 /pmc/articles/PMC9046444/ /pubmed/35497501 http://dx.doi.org/10.1016/j.crmeth.2022.100206 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Preview
Wang, Xin
Sun, Min
Chan, Chung Yu
Wu, Ling-Gang
Phospholipase A(2)-based probes to study vesicle trafficking
title Phospholipase A(2)-based probes to study vesicle trafficking
title_full Phospholipase A(2)-based probes to study vesicle trafficking
title_fullStr Phospholipase A(2)-based probes to study vesicle trafficking
title_full_unstemmed Phospholipase A(2)-based probes to study vesicle trafficking
title_short Phospholipase A(2)-based probes to study vesicle trafficking
title_sort phospholipase a(2)-based probes to study vesicle trafficking
topic Preview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046444/
https://www.ncbi.nlm.nih.gov/pubmed/35497501
http://dx.doi.org/10.1016/j.crmeth.2022.100206
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