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A History of Childhood Maltreatment Has Substance- and Sex-Specific Effects on Craving During Treatment for Substance Use Disorders

RATIONALE: Childhood maltreatment (CM) leads to detrimental mental health outcomes, such as substance use disorders (SUD). This study examined prevalence and severity of all five types of CM with respect to specific substances and sex in treatment-seeking individuals with SUD. The influences of type...

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Autores principales: Gerhardt, Sarah, Eidenmueller, Katharina, Hoffmann, Sabine, Bekier, Nina K., Bach, Patrick, Hermann, Derik, Koopmann, Anne, Sommer, Wolfgang H., Kiefer, Falk, Vollstädt-Klein, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046680/
https://www.ncbi.nlm.nih.gov/pubmed/35492729
http://dx.doi.org/10.3389/fpsyt.2022.866019
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author Gerhardt, Sarah
Eidenmueller, Katharina
Hoffmann, Sabine
Bekier, Nina K.
Bach, Patrick
Hermann, Derik
Koopmann, Anne
Sommer, Wolfgang H.
Kiefer, Falk
Vollstädt-Klein, Sabine
author_facet Gerhardt, Sarah
Eidenmueller, Katharina
Hoffmann, Sabine
Bekier, Nina K.
Bach, Patrick
Hermann, Derik
Koopmann, Anne
Sommer, Wolfgang H.
Kiefer, Falk
Vollstädt-Klein, Sabine
author_sort Gerhardt, Sarah
collection PubMed
description RATIONALE: Childhood maltreatment (CM) leads to detrimental mental health outcomes, such as substance use disorders (SUD). This study examined prevalence and severity of all five types of CM with respect to specific substances and sex in treatment-seeking individuals with SUD. The influences of type of CM and symptoms of depressiveness, anxiety, and perceived stress on substance craving at admission as well as craving reduction during SUD treatment were examined. METHODS: N = 546 patients in treatment for SUD and N = 109 individuals in opioid maintenance treatment filled out questionnaires regarding CM (Childhood Trauma Questionnaire) and psychopathologies. Substance craving was assessed throughout treatment using the Mannheim Craving Scale. Group differences in CM, type of substance and sex were examined. General linear models were applied to examine influences on substance craving. RESULTS: Higher prevalence and severity of all five subtypes of CM were observed in individuals with SUD compared to the general population. Women were more severely affected by emotional and sexual abuse than men. Patients with cannabis use disorder reported more severe experiences of emotional abuse compared to all other substances. Craving at admission to treatment was influenced by emotional abuse, however, symptoms of depressiveness, anxiety, and perceived stress contributed to craving at admission or craving reduction during treatment. CONCLUSION: CM relates to SUD and should be incorporated in prevention and treatment of SUD. Underlying mechanisms of the association might relate to impairments in processing and regulation of stress, emotions, and interpersonal relations following a history of CM.
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spelling pubmed-90466802022-04-29 A History of Childhood Maltreatment Has Substance- and Sex-Specific Effects on Craving During Treatment for Substance Use Disorders Gerhardt, Sarah Eidenmueller, Katharina Hoffmann, Sabine Bekier, Nina K. Bach, Patrick Hermann, Derik Koopmann, Anne Sommer, Wolfgang H. Kiefer, Falk Vollstädt-Klein, Sabine Front Psychiatry Psychiatry RATIONALE: Childhood maltreatment (CM) leads to detrimental mental health outcomes, such as substance use disorders (SUD). This study examined prevalence and severity of all five types of CM with respect to specific substances and sex in treatment-seeking individuals with SUD. The influences of type of CM and symptoms of depressiveness, anxiety, and perceived stress on substance craving at admission as well as craving reduction during SUD treatment were examined. METHODS: N = 546 patients in treatment for SUD and N = 109 individuals in opioid maintenance treatment filled out questionnaires regarding CM (Childhood Trauma Questionnaire) and psychopathologies. Substance craving was assessed throughout treatment using the Mannheim Craving Scale. Group differences in CM, type of substance and sex were examined. General linear models were applied to examine influences on substance craving. RESULTS: Higher prevalence and severity of all five subtypes of CM were observed in individuals with SUD compared to the general population. Women were more severely affected by emotional and sexual abuse than men. Patients with cannabis use disorder reported more severe experiences of emotional abuse compared to all other substances. Craving at admission to treatment was influenced by emotional abuse, however, symptoms of depressiveness, anxiety, and perceived stress contributed to craving at admission or craving reduction during treatment. CONCLUSION: CM relates to SUD and should be incorporated in prevention and treatment of SUD. Underlying mechanisms of the association might relate to impairments in processing and regulation of stress, emotions, and interpersonal relations following a history of CM. Frontiers Media S.A. 2022-04-14 /pmc/articles/PMC9046680/ /pubmed/35492729 http://dx.doi.org/10.3389/fpsyt.2022.866019 Text en Copyright © 2022 Gerhardt, Eidenmueller, Hoffmann, Bekier, Bach, Hermann, Koopmann, Sommer, Kiefer and Vollstädt-Klein. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Psychiatry
Gerhardt, Sarah
Eidenmueller, Katharina
Hoffmann, Sabine
Bekier, Nina K.
Bach, Patrick
Hermann, Derik
Koopmann, Anne
Sommer, Wolfgang H.
Kiefer, Falk
Vollstädt-Klein, Sabine
A History of Childhood Maltreatment Has Substance- and Sex-Specific Effects on Craving During Treatment for Substance Use Disorders
title A History of Childhood Maltreatment Has Substance- and Sex-Specific Effects on Craving During Treatment for Substance Use Disorders
title_full A History of Childhood Maltreatment Has Substance- and Sex-Specific Effects on Craving During Treatment for Substance Use Disorders
title_fullStr A History of Childhood Maltreatment Has Substance- and Sex-Specific Effects on Craving During Treatment for Substance Use Disorders
title_full_unstemmed A History of Childhood Maltreatment Has Substance- and Sex-Specific Effects on Craving During Treatment for Substance Use Disorders
title_short A History of Childhood Maltreatment Has Substance- and Sex-Specific Effects on Craving During Treatment for Substance Use Disorders
title_sort history of childhood maltreatment has substance- and sex-specific effects on craving during treatment for substance use disorders
topic Psychiatry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046680/
https://www.ncbi.nlm.nih.gov/pubmed/35492729
http://dx.doi.org/10.3389/fpsyt.2022.866019
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