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TNF-α-Secreting Lung Tumor-Infiltrated Monocytes Play a Pivotal Role During Anti-PD-L1 Immunotherapy

Immune checkpoint blockade (ICB) of the PD-1 pathway revolutionized the survival forecast for advanced non-small cell lung cancer (NSCLC). Yet, the majority of PD-L1(+) NSCLC patients are refractory to anti-PD-L1 therapy. Recent observations indicate a pivotal role for the PD-L1(+) tumor-infiltratin...

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Detalles Bibliográficos
Autores principales: De Ridder, Kirsten, Locy, Hanne, Piccioni, Elisa, Zuazo, Miren Ibarra, Awad, Robin Maximilian, Verhulst, Stefaan, Van Bulck, Mathias, De Vlaeminck, Yannick, Lecocq, Quentin, Reijmen, Eva, De Mey, Wout, De Beck, Lien, Ertveldt, Thomas, Pintelon, Isabel, Timmermans, Jean-Pierre, Escors, David, Keyaerts, Marleen, Breckpot, Karine, Goyvaerts, Cleo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046849/
https://www.ncbi.nlm.nih.gov/pubmed/35493461
http://dx.doi.org/10.3389/fimmu.2022.811867