Cargando…
Hypothalamic Irak4 is a genetically controlled regulator of hypoglycemia-induced glucagon secretion
OBJECTIVES: Glucagon secretion to stimulate hepatic glucose production is the first line of defense against hypoglycemia. This response is triggered by so far incompletely characterized central hypoglycemia-sensing mechanisms, which control autonomous nervous activity and hormone secretion. The obje...
Autores principales: | Picard, Alexandre, Berney, Xavier, Castillo-Armengol, Judit, Tarussio, David, Jan, Maxime, Sanchez-Archidona, Ana Rodriguez, Croizier, Sophie, Thorens, Bernard |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046887/ https://www.ncbi.nlm.nih.gov/pubmed/35339728 http://dx.doi.org/10.1016/j.molmet.2022.101479 |
Ejemplares similares
-
Fgf15 Neurons of the Dorsomedial Hypothalamus Control Glucagon Secretion and Hepatic Gluconeogenesis
por: Picard, Alexandre, et al.
Publicado: (2021) -
Lipid biosynthesis enzyme Agpat5 in AgRP-neurons is required for insulin-induced hypoglycemia sensing and glucagon secretion
por: Strembitska, Anastasiya, et al.
Publicado: (2022) -
A Genetic Screen Identifies Hypothalamic Fgf15 as a Regulator of Glucagon Secretion
por: Picard, Alexandre, et al.
Publicado: (2016) -
Tmem117 in AVP neurons regulates the counterregulatory response to hypoglycemia
por: Gaspari, Sevasti, et al.
Publicado: (2023) -
Klf6 protects β-cells against insulin resistance-induced dedifferentiation
por: Dumayne, Christopher, et al.
Publicado: (2020)