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Single-cell multi-omics analysis reveals IFN-driven alterations in T lymphocytes and natural killer cells in systemic lupus erythematosus

Background: The characterisation of the peripheral immune system in the autoimmune disease systemic lupus erythematosus (SLE) at the single-cell level has been limited by the reduced sensitivity of current whole-transcriptomic technologies. Here we employ a targeted single-cell multi-omics approach,...

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Detalles Bibliográficos
Autores principales:	Trzupek, Dominik, Lee, Mercede, Hamey, Fiona, Wicker, Linda S., Todd, John A., Ferreira, Ricardo C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	F1000 Research Limited 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046903/ https://www.ncbi.nlm.nih.gov/pubmed/35509371 http://dx.doi.org/10.12688/wellcomeopenres.16883.2

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