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DNA polymerase η promotes nonhomologous end joining upon etoposide exposure dependent on the scaffolding protein Kap1

DNA polymerase eta (Pol η) is a eukaryotic member of the Y-family of DNA polymerase involved in translesion DNA synthesis and genome mutagenesis. Recently, several translesion DNA synthesis polymerases have been found to function in repair of DNA double-strand breaks (DSBs). However, the role of Pol...

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Detalles Bibliográficos
Autores principales:	Ma, Xiaolu, Wang, Chen, Zhou, Bo, Cheng, Zina, Mao, Zhiyong, Tang, Tie-Shan, Guo, Caixia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046958/ https://www.ncbi.nlm.nih.gov/pubmed/35339488 http://dx.doi.org/10.1016/j.jbc.2022.101861

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