Potential Application of Tea Polyphenols to the Prevention of COVID-19 Infection: Based on the Gut-Lung Axis

Coronavirus disease 2019 (COVID-19) disrupts the intestinal micro-ecological balance, and patients often develop the intestinal disease. The gut is the largest immune organ in the human body; intestinal microbes can affect the immune function of the lungs through the gut-lung axis. It has been repor...

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Autores principales: Xu, Lei, Ho, Chi-Tang, Liu, Yanan, Wu, Zufang, Zhang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Nutrition
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046984/
https://www.ncbi.nlm.nih.gov/pubmed/35495940
http://dx.doi.org/10.3389/fnut.2022.899842
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author Xu, Lei
Ho, Chi-Tang
Liu, Yanan
Wu, Zufang
Zhang, Xin
author_facet Xu, Lei
Ho, Chi-Tang
Liu, Yanan
Wu, Zufang
Zhang, Xin
author_sort Xu, Lei
collection PubMed
description Coronavirus disease 2019 (COVID-19) disrupts the intestinal micro-ecological balance, and patients often develop the intestinal disease. The gut is the largest immune organ in the human body; intestinal microbes can affect the immune function of the lungs through the gut-lung axis. It has been reported that tea polyphenols (TPs) have antiviral and prebiotic activity. In this review, we discussed TPs reduced lung-related diseases through gut-lung axis by inhibiting dysbiosis. In addition, we also highlighted the preventive and therapeutic effects of TPs on COVID-19 complications, further demonstrating the importance of research on TPs for the prevention and treatment of COVID-19 in humans. Based on this understanding, we recommend using TPs to regulate the gut microbiota to prevent or alleviate COVID-19 through the gut-lung axis.
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spelling pubmed-90469842022-04-29 Potential Application of Tea Polyphenols to the Prevention of COVID-19 Infection: Based on the Gut-Lung Axis Xu, Lei Ho, Chi-Tang Liu, Yanan Wu, Zufang Zhang, Xin Front Nutr Nutrition Coronavirus disease 2019 (COVID-19) disrupts the intestinal micro-ecological balance, and patients often develop the intestinal disease. The gut is the largest immune organ in the human body; intestinal microbes can affect the immune function of the lungs through the gut-lung axis. It has been reported that tea polyphenols (TPs) have antiviral and prebiotic activity. In this review, we discussed TPs reduced lung-related diseases through gut-lung axis by inhibiting dysbiosis. In addition, we also highlighted the preventive and therapeutic effects of TPs on COVID-19 complications, further demonstrating the importance of research on TPs for the prevention and treatment of COVID-19 in humans. Based on this understanding, we recommend using TPs to regulate the gut microbiota to prevent or alleviate COVID-19 through the gut-lung axis. Frontiers Media S.A. 2022-04-14 /pmc/articles/PMC9046984/ /pubmed/35495940 http://dx.doi.org/10.3389/fnut.2022.899842 Text en Copyright © 2022 Xu, Ho, Liu, Wu and Zhang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Nutrition
Xu, Lei
Ho, Chi-Tang
Liu, Yanan
Wu, Zufang
Zhang, Xin
Potential Application of Tea Polyphenols to the Prevention of COVID-19 Infection: Based on the Gut-Lung Axis
title Potential Application of Tea Polyphenols to the Prevention of COVID-19 Infection: Based on the Gut-Lung Axis
title_full Potential Application of Tea Polyphenols to the Prevention of COVID-19 Infection: Based on the Gut-Lung Axis
title_fullStr Potential Application of Tea Polyphenols to the Prevention of COVID-19 Infection: Based on the Gut-Lung Axis
title_full_unstemmed Potential Application of Tea Polyphenols to the Prevention of COVID-19 Infection: Based on the Gut-Lung Axis
title_short Potential Application of Tea Polyphenols to the Prevention of COVID-19 Infection: Based on the Gut-Lung Axis
title_sort potential application of tea polyphenols to the prevention of covid-19 infection: based on the gut-lung axis
topic Nutrition
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046984/
https://www.ncbi.nlm.nih.gov/pubmed/35495940
http://dx.doi.org/10.3389/fnut.2022.899842
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