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Elevated Expression of TLR2 in Aging Hearts Exacerbates Cardiac Inflammatory Response and Adverse Remodeling Following Ischemia and Reperfusion Injury

This study tested the hypothesis that Toll-like receptor 2 (TLR2) augments the inflammatory responses and adverse remodeling in aging hearts to exacerbate myocardial injury and cardiac dysfunction. METHODS: Old (20-22 months old) and adult (4-6 months old) mice of C57BL/6 wild-type and TLR2 knockout...

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Detalles Bibliográficos
Autores principales:	Zhai, Yufeng, Ao, Lihua, Yao, Qingzhou, The, Erlinda, Fullerton, David A., Meng, Xianzhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046986/ https://www.ncbi.nlm.nih.gov/pubmed/35493479 http://dx.doi.org/10.3389/fimmu.2022.891570

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