Identification of H(2)S/NO-donating artemisinin derivatives as potential antileukemic agents

Three H(2)S/NO-donating artemisinin derivatives were designed and synthesized. Their antiproliferative activities were evaluated against human acute myeloid leukemia (AML) cell lines of K562 and K562/ADR and human normal liver cells of LO2. Biological evaluation indicated that NO-donating compound 1...

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Detalles Bibliográficos
Autores principales: Chen, Xuemei, Huang, Pei, Wang, Jing, Tian, Runmei, Chen, Yan, Chen, Yongzheng, Zhang, Lei, Ma, Zhigui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9047252/
https://www.ncbi.nlm.nih.gov/pubmed/35492518
http://dx.doi.org/10.1039/c9ra08239e

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